← Mechanisms of action
Phosphodiesterase 4
PROTEIN FAMILYHomo sapiens
Linked proteins
Drugs acting on this target (24)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| aminophylline (aminophyllin) | Inhibitor | approved | Small molecule | Phosphodiesterase 4 inhibitor |
| amlexanox (aphthasol) | Inhibitor | approved | Small molecule | Phosphodiesterase 4 inhibitor |
| an2898 | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |
| apremilast (otezla) | Inhibitor | approved | Small molecule | Phosphodiesterase 4 inhibitor |
| Cilomilast | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |
| crisaborole (eucrisa) | Inhibitor | approved | Small molecule | Phosphodiesterase 4 inhibitor |
| Difamilast | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |
| dovramilast | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |
| Drotaverine | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |
| dyphylline (neothylline) | Inhibitor | approved | Small molecule | Phosphodiesterase 4 inhibitor |
| ensifentrine (Ohtuvayre) | Inhibitor | approved | Small molecule | Phosphodiesterase 4 inhibitor |
| flavoxate (urispas) | Inhibitor | approved | Small molecule | Phosphodiesterase 4 inhibitor |
| gsk-256066 | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |
| ht-0712 | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |
| ibudilast | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |
| mk-0873 | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |
| oglemilast | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |
| oxtriphylline (choledyl) | Inhibitor | approved | Small molecule | Phosphodiesterase 4 inhibitor |
| revamilast | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |
| roflumilast (daliresp) | Inhibitor | approved | Small molecule | Phosphodiesterase 4 inhibitor |
| Rolipram | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |
| tetomilast | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |
| theophylline (synophylate) | Inhibitor | approved | Small molecule | Phosphodiesterase 4 inhibitor |
| tofimilast | Inhibitor | experimental | Small molecule | Phosphodiesterase 4 inhibitor |