3',5'-cyclic phosphodiesterase

PROTEIN FAMILYHomo sapiens

Linked proteins

cGMP-specific 3',5'-cyclic phosphodiesterase (PDE5A) ↗
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (PDE4A) ↗
cGMP-inhibited 3',5'-cyclic phosphodiesterase A (PDE3A) ↗
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (PDE6H) ↗
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (PDE6G) ↗
cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A) ↗
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (PDE7A) ↗
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (PDE1A) ↗
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (PDE9A) ↗
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (PDE6B) ↗
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (PDE4D) ↗
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B) ↗
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) ↗
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (PDE6A) ↗
cGMP-inhibited 3',5'-cyclic phosphodiesterase B (PDE3B) ↗
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (PDE6C) ↗
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (PDE8B) ↗
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A) ↗
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (PDE1B) ↗
cAMP-specific 3',5'-cyclic phosphodiesterase 4C (PDE4C) ↗
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (PDE1C) ↗
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (PDE8A) ↗
cAMP-specific 3',5'-cyclic phosphodiesterase 7B (PDE7B) ↗

Drugs acting on this target (1)

Active Pharmaceutical Ingredient	Mechanism Type ▲	Approval Status	API Type	Mechanism of Action
dipyridamole (persantine)	Inhibitor	approved	Small molecule	3',5'-cyclic phosphodiesterase inhibitor