← Mechanisms of action
CHRM2
SINGLE PROTEINHomo sapiens
Preferred name: Muscarinic acetylcholine receptor M2 ChEMBL ↗
Linked proteins
Drugs acting on this target (19)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| bethanechol (urecholine) | Agonist | approved | Small molecule | CHRM2 agonist |
| asm-024 | Antagonist | experimental | Small molecule | CHRM2 antagonist |
| atropine | Antagonist | approved | Small molecule | CHRM2 antagonist |
| batefenterol | Antagonist | experimental | Small molecule | CHRM2 antagonist |
| darifenacin (enablex) | Antagonist | approved | Small molecule | CHRM2 antagonist |
| fesoterodine (toviaz) | Antagonist | approved | Small molecule | CHRM2 antagonist |
| oxitropium (Oxivent) | Antagonist | experimental | Small molecule | CHRM2 antagonist |
| oxybutynin (ditropan) | Antagonist | approved | Small molecule | CHRM2 antagonist |
| propantheline bromide (pro-banthine) | Antagonist | approved | Small molecule | CHRM2 antagonist |
| qax028 | Antagonist | experimental | Small molecule | CHRM2 antagonist |
| solifenacin (vesicare) | Antagonist | approved | Small molecule | CHRM2 antagonist |
| tolterodine (detrol) | Antagonist | approved | Small molecule | CHRM2 antagonist |
| trospium (sanctura) | Antagonist | approved | Small molecule | CHRM2 antagonist |
| Acotiamide | Inhibitor | experimental | Small molecule | CHRM2 inhibitor |
| aroxybutynin | Inhibitor | experimental | Small molecule | CHRM2 inhibitor |
| nifekalant | Inhibitor | experimental | Small molecule | CHRM2 inhibitor |
| r-oxybutynin | Inhibitor | experimental | Small molecule | CHRM2 inhibitor |
| talsaclidine | Partial agonist | experimental | Small molecule | Muscarinic acetylcholine receptor M2 partial agonist |
| diallyltoxiferine | Positive allosteric modulator | experimental | Small molecule | CHRM2 positive allosteric modulator |