CDEK
← Mechanisms of action

MAP2K1

SINGLE PROTEINHomo sapiens
Preferred name: Dual specificity mitogen-activated protein kinase kinase 1 ChEMBL ↗

Linked proteins

Drugs acting on this target (34)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
abm-168InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
amo-01InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
as-703988InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
astx029InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
avutometinib (Avmapki fakzynja)InhibitorapprovedSmall moleculeMAP2K1 inhibitor
azd-8330InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
balamapimodInhibitorexperimentalSmall moleculeMAP2K1 inhibitor
bi 847325InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
binimetinib (mektovi)InhibitorapprovedSmall moleculeMAP2K1 inhibitor
cc-90003InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
ci-1040InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
cobimetinib (cotellic)InhibitorapprovedSmall moleculeMAP2K1 inhibitor
cs3006InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
e-6201InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
felbamate (Felbatol)InhibitorapprovedSmall moleculeMAP2K1 inhibitor
gingko bilobaInhibitorexperimentalBotanicalMAP2K1 inhibitor
hl-085InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
hrs2543InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
imm-1-104InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
imm-6-415InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
ko-947InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
LNP3794InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
mirdametinib (Gomekli)InhibitorapprovedSmall moleculeMAP2K1 inhibitor
pas-004InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
pimasertibInhibitorexperimentalSmall moleculeMAP2K1 inhibitor
rec-4881InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
refametinibInhibitorexperimentalSmall moleculeMAP2K1 inhibitor
ro-4987655InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
selumetinib (Koselugo)InhibitorapprovedSmall moleculeMAP2K1 inhibitor
shr7390InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
tak-733InhibitorexperimentalSmall moleculeMAP2K1 inhibitor
trametinib (mekinist)InhibitorapprovedSmall moleculeMAP2K1 inhibitor
tunlametinibInhibitorexperimentalSmall moleculeMAP2K1 inhibitor
zapnometinibInhibitorexperimentalSmall moleculeMAP2K1 inhibitor