gingko biloba
Botanicalexperimental
Ginkgo biloba, commonly known as ginkgo, also known as the maidenhair tree, and often misspelled "gingko" is a species of gymnosperm tree native to East Asia. It is the last living species in the order Ginkgoales, which first appeared over 290 million years ago. Fossils similar to the living species, belonging to the genus Ginkgo, extend back to the Middle Jurassic epoch approximately 170 million years ago. The tree was cultivated early in human history, remains commonly planted, and is widely regarded as a living fossil. — Wikipedia
Clinical trial activity
20 trials · 30 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
13
Phase 3
6
Phase 4
2
Earliest trial started Jul 1, 2001 (NCT00070161)
Timeline
Indications
Approved for
Studied for
- Aging · Phase 2
- Alzheimer Disease · Phase 2
- Brain Neoplasms · Phase 2
- Cerebrovascular Disorders · Phase 2
- Cognition Disorders · Phase 4
- Cognitive Dysfunction · Phase 2
- Diabetes Mellitus · Phase 3
- Drug-Related Side Effects and Adverse Reactions · Phase 2
- Friedreich Ataxia · Phase 2
- Memory Disorders · Phase 4
- Mental Disorders · Phase 3
- Multiple Sclerosis, Relapsing-Remitting · Phase 3
- Schizophrenia · Phase 3
- Stroke · Phase 3
- Tardive Dyskinesia · Phase 3
- Urological Manifestations · Phase 3
Mechanism of action
MAP2K1 inhibitor
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaGinkgo biloba ↗
- NCATS1XUK686051 ↗
Also known as
- egb761
- egb761
- egb761
- egb 761
- egb-761
- gbe 761
- gbe-761
- gbe 761 onc
- gingko biloba extract
- ginkgo biloba extract
- ginkgo biloba extract
- ginkgo biloba extract 761
- ginkgo leaf extract
- rokan
- tanakan
- tebofortran
- tebokan
- tebonin
- yy-162
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06989697 | Phase 3 | Jan 1, 2025 | Seoul National University, SK Chemicals |
| NCT06583941 | N/A | Sep 30, 2024 | Lonza |
| NCT05594355 | Phase 4 | Apr 16, 2021 | Fundació ACE |
| NCT04525144 | Phase 2 | Sep 30, 2020 | National Neuroscience Institute, Schwabe |
| NCT04499157 | N/A | Aug 31, 2020 | University of Picardie Jules Verne |
| NCT04492241 | N/A | Aug 1, 2020 | Beijing Stroke Association, Capital Medical University |
| NCT04448535 | N/A | Jul 31, 2020 | State University of New York |
| NCT03761992 | N/A | Nov 19, 2018 | Icahn School of Medicine at Mount Sinai |
| NCT03647384 | Phase 2 | Aug 22, 2018 | Beijing Xuanwu Traditional Chinese Medicine Hospital, Capital Medical University, China Academy of Chinese Medical Sciences, Chinese Academy of Medical Sciences, Fudan University, Henan Medical University, Peking University, Shaanxi University of Chinese Medicine, Shandong University, Shanghai University, Shanxi Medical University |
| NCT03228550 | Phase 2 | Feb 26, 2017 | Bournemouth University, Efamol Ltd, Sylvia Waddilove Foundation |
| NCT01536210 | Phase 3 | Dec 1, 2011 | Hallym University, Inje University, Seoul National University, Yuyu Pharma, Inc. |
| NCT01201187 | Phase 3 | Mar 1, 2010 | Hallym University, Inje University, Seoul National University, Yuyu Pharma, Inc. |
| NCT00814346 | Phase 2 | Oct 1, 2008 | Ipsen |
| NCT00824512 | Phase 2 | Jun 1, 2008 | Ipsen |
| NCT00672373 | Phase 3 | Dec 1, 2006 | Peking University |
| NCT00500500 | Phase 2 | Jul 1, 2005 | Ipsen |
| NCT00276341 | Phase 3 | Aug 1, 2003 | Ipsen |
| NCT00276380 | Phase 3 | Feb 1, 2003 | Ipsen |
| NCT00276510 | Phase 4 | Feb 1, 2002 | Ipsen |
| NCT00070161 | Phase 2 | Jul 1, 2001 | National Cancer Institute (NCI), Wake Forest University |
Showing 20 of 20 trials
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Organizations
Research & Development (30)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Ipsen | For profit | 6 | 6 | 3 | 2002 |
| Seoul National University | Academic/Hospital | 3 | 1 | 1 | 2010 |
| Capital Medical University | Academic/Hospital | 2 | 1 | 2 | 2018 |
| Hallym University | Academic/Hospital | 2 | 0 | 1 | 2010 |
| Inje University | Academic/Hospital | 2 | 0 | 1 | 2010 |
| Peking University | Academic/Hospital | 2 | 1 | 2 | 2006 |
| Yuyu Pharma, Inc. | For profit | 2 | 2 | 1 | 2010 |
| Beijing Stroke Association | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Beijing Xuanwu Traditional Chinese Medicine Hospital | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Bournemouth University | Academic/Hospital | 1 | 1 | 1 | 2017 |
| China Academy of Chinese Medical Sciences | Academic/Hospital | 1 | 1 | 1 | 2018 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Efamol Ltd | For profit | 1 | 0 | 1 | 2017 |
| Fudan University | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Fundació ACE | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Henan Medical University | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Icahn School of Medicine at Mount Sinai | Academic/Hospital | 1 | 1 | 1 | 2018 |
| Lonza | For profit | 1 | 1 | 1 | 2024 |
| National Cancer Institute (NCI) | Government | 1 | 0 | 1 | 2001 |
| National Neuroscience Institute | Government | 1 | 1 | 1 | 2020 |
30 organizations
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