CD274

SINGLE PROTEINHomo sapiens

Preferred name: Programmed cell death 1 ligand 1 ChEMBL ↗

Linked proteins

Programmed cell death 1 ligand 1 (CD274) ↗

Drugs acting on this target (158)

Active Pharmaceutical Ingredient	Mechanism Type ▲	Approval Status	API Type	Mechanism of Action
6mw3211	Antagonist	experimental	mAb	PDL1
abl501	Antagonist	experimental	mAb	PDL1
abl503	Antagonist	experimental	mAb	PDL1
ak129	Antagonist	experimental	mAb	PDL1
asc22	Antagonist	experimental	mAb	PDL1
atezolizumab (Tecentriq)	Antagonist	approved	mAb	PD-L1
atg-101	Antagonist	experimental	mAb	PDL1
b1962	Antagonist	experimental	mAb	PDL1
bj-005	Antagonist	experimental	mAb	PDL1
bpi-371153	Antagonist	experimental	Small molecule	PDL1
bpi-421286	Antagonist	experimental	Small molecule	PDL1
emb-09	Antagonist	experimental	mAb	PDL1
FS-118	Antagonist	experimental	mAb	PDL1
FS-222	Antagonist	experimental	mAb	PDL1
fs222	Antagonist	experimental	mAb	PDL1
gnc-035	Antagonist	experimental	mAb	PDL1
gnc-038	Antagonist	experimental	mAb	PDL1
gnc-039	Antagonist	experimental	mAb	PDL1
hb0036	Antagonist	experimental	mAb	PDL1
hlx301	Antagonist	experimental	mAb	PDL1
ibc-ab002	Antagonist	experimental	mAb	PDL1
IBI 323	Antagonist	experimental	mAb	PDL1
ibi-322	Antagonist	experimental	mAb	PDL1
ibi323	Antagonist	experimental	mAb	PDL1
pf-07257876	Antagonist	experimental	mAb	PDL1
PM-8001	Antagonist	experimental	mAb	PDL1
pm8002	Antagonist	experimental	mAb	CD274 antagonist
prs-344	Antagonist	experimental	mAb	PDL1
q-1802	Antagonist	experimental	mAb	PDL1
qlf31907	Antagonist	experimental	mAb	PDL1
qlf32004	Antagonist	experimental	mAb	PDL1
qls31901	Antagonist	experimental	mAb	PDL1
s095012	Antagonist	experimental	mAb	PDL1
TQ-B2858	Antagonist	experimental	mAb	PDL1
tqb2450	Antagonist	experimental	mAb	PDL1
tqb2858	Antagonist	experimental	Recombinant protein	CD274 antagonist
dcr-pdl1	Antisense inhibitor	experimental	Nucleic acid	CD274 antisense inhibitor
bintrafusp alfa	Binding agent	experimental	Recombinant protein	Programmed cell death 1 ligand 1 binding agent
cs1001	Binding agent	experimental	mAb	Programmed cell death 1 ligand 1 binding agent
envafolimab	Binding agent	experimental	mAb	Programmed cell death 1 ligand 1 binding agent
sgn-pdl1v	Binding agent	experimental	mAb	PDL1
b7-1	Immunity, active	experimental	Vaccine	CD274 immunity, active
ido peptide	Immunity, active	experimental	Vaccine	CD274 immunity, active
mrna-4359	Immunity, active	experimental	Vaccine	CD274 immunity, active
pd-l1 peptide vaccine	Immunity, active	experimental	Vaccine	CD274 immunity, active
pd-l1/ido peptide vaccine	Immunity, active	experimental	Vaccine	CD274 immunity, active
pd-l2 and pd-l1 peptide	Immunity, active	experimental	Vaccine	CD274 immunity, active
dual-targeting cldn18.2 and pd-l1 car-t cells	Immunity, passive	experimental	Cell therapy	CD274 immunity, passive
mgd013	Immunity, passive	experimental	mAb	CD274 immunity, passive
pd-1-m1-nk cells	Immunity, passive	experimental	Cell therapy	CD274 immunity, passive
pd-l1 car-t cell	Immunity, passive	experimental	Cell therapy	CD274 immunity, passive
pd1-til	Immunity, passive	experimental	Cell therapy	CD274 immunity, passive
tqb2450	Immunity, passive	experimental	mAb	CD274 immunity, passive
α-pd-l1/4-1bb dll3 car-t (bhp01)	Immunity, passive	experimental	Cell therapy	CD274 immunity, passive
89zr˗dfo˗regn3504	Inhibitor	experimental	mAb	CD274 inhibitor
abs-201	Inhibitor	experimental	mAb	CD274 inhibitor
absk043	Inhibitor	experimental	Small molecule	CD274 inhibitor
adebrelimab	Inhibitor	experimental	Small molecule	CD274 inhibitor
ai-081	Inhibitor	experimental	mAb	CD274 inhibitor
an4005	Inhibitor	experimental	Small molecule	CD274 inhibitor
ap203	Inhibitor	experimental	mAb	CD274 inhibitor
ap505	Inhibitor	experimental	mAb	CD274 inhibitor
asc61	Inhibitor	experimental	Small molecule	CD274 inhibitor
atezolizumab (Tecentriq)	Inhibitor	approved	mAb	CD274 inhibitor
avelumab (bavencio)	Inhibitor	approved	mAb	CD274 inhibitor
axn-2510	Inhibitor	experimental	mAb	CD274 inhibitor
bcd-135	Inhibitor	experimental	mAb	CD274 inhibitor
bgb-a333	Inhibitor	experimental	mAb	CD274 inhibitor
bh3120	Inhibitor	experimental	mAb	CD274 inhibitor
bintrafusp alfa	Inhibitor	experimental	Recombinant protein	CD274 inhibitor
bms-936559	Inhibitor	experimental	mAb	CD274 inhibitor
bms-986189	Inhibitor	experimental	Peptide	CD274 inhibitor
BMS-986192	Inhibitor	experimental	mAb	CD274 inhibitor
bnt327	Inhibitor	experimental	mAb	CD274 inhibitor
bpb-101	Inhibitor	experimental	mAb	CD274 inhibitor
ca-170	Inhibitor	experimental	Small molecule	CD274 inhibitor
cn202	Inhibitor	experimental	mAb	CD274 inhibitor
compound 2055269	Inhibitor	experimental	mAb	CD274 inhibitor
cosibelimab (Unloxcyt)	Inhibitor	approved	mAb	Programmed cell death 1 ligand 1 inhibitor
cs1001	Inhibitor	experimental	mAb	CD274 inhibitor
ctx-8371	Inhibitor	experimental	mAb	CD274 inhibitor
cvl006	Inhibitor	experimental	mAb	CD274 inhibitor
cx-072	Inhibitor	experimental	mAb	CD274 inhibitor
db-1419	Inhibitor	experimental	mAb	CD274 inhibitor
dk222	Inhibitor	experimental	Peptide	CD274 inhibitor
dr30206	Inhibitor	experimental	mAb	CD274 inhibitor
durvalumab (imfinzi)	Inhibitor	approved	mAb	CD274 inhibitor
engineered erythrocytes (or red blood cells) covalently conjugated with commercially available anti-pd-1 antibodies on their membranes	Inhibitor	experimental	Cell therapy	CD274 inhibitor
envafolimab	Inhibitor	experimental	mAb	CD274 inhibitor
es101	Inhibitor	experimental	mAb	CD274 inhibitor
Evixapodlin	Inhibitor	experimental	Small molecule	CD274 inhibitor
faz053	Inhibitor	experimental	mAb	CD274 inhibitor
fs118	Inhibitor	experimental	mAb	CD274 inhibitor
gen1046	Inhibitor	experimental	mAb	CD274 inhibitor
gen1056	Inhibitor	experimental	mAb	CD274 inhibitor
gr1405	Inhibitor	experimental	mAb	CD274 inhibitor
gx-p1	Inhibitor	experimental	mAb	CD274 inhibitor
hb0025	Inhibitor	experimental	mAb	CD274 inhibitor
hb0028	Inhibitor	experimental	mAb	CD274 inhibitor
hcb301	Inhibitor	experimental	Recombinant protein	CD274 inhibitor
hlx20	Inhibitor	experimental	mAb	CD274 inhibitor
hlx37	Inhibitor	experimental	mAb	CD274 inhibitor
hlx43	Inhibitor	experimental	mAb	CD274 inhibitor
hy05350	Inhibitor	experimental	mAb	CD274 inhibitor
hy07121	Inhibitor	experimental	mAb	CD274 inhibitor
ibi-322	Inhibitor	experimental	mAb	CD274 inhibitor
ibi3014	Inhibitor	experimental	mAb	CD274 inhibitor
ibi318	Inhibitor	experimental	mAb	CD274 inhibitor
igm-7354	Inhibitor	experimental	mAb	CD274 inhibitor
imc001	Inhibitor	experimental	mAb	CD274 inhibitor
imgs-001	Inhibitor	experimental	mAb	CD274 inhibitor
imm2510	Inhibitor	experimental	Recombinant protein	CD274 inhibitor
imm2520	Inhibitor	experimental	mAb	CD274 inhibitor
IMMH-010	Inhibitor	experimental	Small molecule	CD274 inhibitor
inbrx-105	Inhibitor	experimental	mAb	CD274 inhibitor
incb086550	Inhibitor	experimental	Small molecule	CD274 inhibitor
incb099280	Inhibitor	experimental	Small molecule	CD274 inhibitor
ivocizumab	Inhibitor	experimental	mAb	CD274 inhibitor
jskn022	Inhibitor	experimental	mAb	CD274 inhibitor
kd033	Inhibitor	experimental	Recombinant protein	CD274 inhibitor
kl-a167	Inhibitor	experimental	mAb	CD274 inhibitor
kn046	Inhibitor	experimental	mAb	CD274 inhibitor
lb101	Inhibitor	experimental	mAb	CD274 inhibitor
lbl-024	Inhibitor	experimental	Small molecule	CD274 inhibitor
ldp	Inhibitor	experimental	mAb	CD274 inhibitor
lp002	Inhibitor	experimental	mAb	CD274 inhibitor
ly3300054	Inhibitor	experimental	mAb	CD274 inhibitor
ly3415244	Inhibitor	experimental	mAb	CD274 inhibitor
ly3434172	Inhibitor	experimental	mAb	CD274 inhibitor
max-10181	Inhibitor	experimental	Small molecule	CD274 inhibitor
mcla-145	Inhibitor	experimental	mAb	CD274 inhibitor
mdx1105-01	Inhibitor	experimental	mAb	CD274 inhibitor
msb0011359c	Inhibitor	experimental	mAb	CD274 inhibitor
msb2311	Inhibitor	experimental	mAb	CD274 inhibitor
mt-6402	Inhibitor	experimental	Recombinant protein	CD274 inhibitor
nm21-1480	Inhibitor	experimental	mAb	CD274 inhibitor
ose-279	Inhibitor	experimental	mAb	CD274 inhibitor
pd-l1/ctla4 bsab	Inhibitor	experimental	mAb	CD274 inhibitor
pf-08046037	Inhibitor	experimental	mAb	CD274 inhibitor
pf-08046054	Inhibitor	experimental	mAb	CD274 inhibitor
pm1003	Inhibitor	experimental	mAb	CD274 inhibitor
pm1022	Inhibitor	experimental	mAb	CD274 inhibitor
rc198	Inhibitor	experimental	mAb	CD274 inhibitor
sctb14	Inhibitor	experimental	mAb	CD274 inhibitor
sh006	Inhibitor	experimental	mAb	CD274 inhibitor
shr-1701	Inhibitor	experimental	Recombinant protein	CD274 inhibitor
sim0237	Inhibitor	experimental	mAb	CD274 inhibitor
soa101	Inhibitor	experimental	mAb	CD274 inhibitor
spx-303	Inhibitor	experimental	mAb	CD274 inhibitor
ssgj-706	Inhibitor	experimental	mAb	CD274 inhibitor
ssgj-707	Inhibitor	experimental	mAb	CD274 inhibitor
tagitanlimab	Inhibitor	experimental	mAb	CD274 inhibitor
tg-1501	Inhibitor	experimental	mAb	CD274 inhibitor
xb628	Inhibitor	experimental	mAb	CD274 inhibitor
Y101D	Inhibitor	experimental	mAb	CD274 inhibitor
zkab001	Inhibitor	experimental	mAb	CD274 inhibitor
avelumab (bavencio)	Other	approved	mAb	CD274 other
[68ga]ga-nota-rnd20	Radiopharmaceutical	experimental	Small molecule	CD274 radiopharmaceutical