gnc-038
mAbexperimentalQuad-specific
Clinical trial activity
7 trials · 8 clinical orgs · 0 marketing orgs
Phase 1
7
Phase 2
4
Phase 3
0
Phase 4
0
Earliest trial started Nov 30, 2020 (NCT04606433)
Timeline
2020s
- Jan 1, 2020
Earliest Phase 1 Sponsor(trial)
Indications
Mechanism of action
CD3E agonist
TNFRSF9 antagonist
- Programmed cell death 1 ligand 1ANTAGONIST
PDL1
- B-lymphocyte antigen CD19BINDING AGENT
CD19
Chemistry & pharmacology
- Multi-specific
- Yes (Quad-specific)
Oral
No
Parenteral
No
Topical
No
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06857227 | Phase 1 | Mar 31, 2025 | Baili Pharmaceutical Group |
| NCT06857214 | Phase 1 | Mar 31, 2025 | Baili Pharmaceutical Group |
| NCT05623982 | Phase 1/Phase 2 (Phase 2) | Dec 31, 2022 | Baili Pharmaceutical Group, Peking University, SystImmune Inc. |
| NCT05627856 | Phase 1/Phase 2 (Phase 2) | Nov 30, 2022 | Baili Pharmaceutical Group, Shantou University, Sun Yat-Sen University, SystImmune Inc. |
| NCT05485753 | Phase 1/Phase 2 (Phase 2) | Feb 14, 2022 | Baili Pharmaceutical Group, Capital Medical University, SystImmune Inc. |
| NCT05192486 | Phase 1/Phase 2 (Phase 2) | Dec 14, 2021 | Baili Pharmaceutical Group, Jiao Tong University, SystImmune Inc. |
| NCT04606433 | Phase 1 | Nov 30, 2020 | Baili Pharmaceutical Group, Chinese Academy of Medical Sciences, SystImmune Inc. |
Showing 7 of 7 trials
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Organizations
Research & Development (8)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Baili Pharmaceutical Group | For profit | 7 | 7 | 2 | 2020 |
| SystImmune Inc. | For profit | 5 | 0 | 2 | 2020 |
| Capital Medical University | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Jiao Tong University | Academic/Hospital | 1 | 0 | 1 | 2021 |
| Peking University | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Shantou University | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Sun Yat-Sen University | Academic/Hospital | 1 | 0 | 1 | 2022 |
8 organizations
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