pm8002
mAbexperimentalBi-specific
Clinical trial activity
13 trials · 10 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
11
Phase 3
4
Phase 4
0
Earliest trial started Mar 9, 2021 (NCT05918445)
Timeline
Indications
Studied for
Mechanism of action
- Vascular endothelial growth factor AANTAGONIST
VEGFA antagonist
- Programmed cell death 1 ligand 1ANTAGONIST
CD274 antagonist
Chemistry & pharmacology
- Multi-specific
- Yes (Bi-specific)
Oral
No
Parenteral
No
Topical
No
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07133750 | Phase 2 | Aug 31, 2025 | Biontech, Biotheus, Sun Yat-Sen University |
| NCT06837948 | Phase 2 | Feb 18, 2025 | Huazhong University of Science and Technology |
| NCT06584071 | Phase 1/Phase 2 (Phase 2) | Oct 31, 2024 | Biotheus, Fudan University |
| NCT06616532 | Phase 3 | Oct 25, 2024 | Biotheus, Jilin Provincial Tumor Hospital |
| NCT06419621 | Phase 3 | Jun 11, 2024 | Biotheus, Fudan University |
| NCT05844150 | Phase 2/Phase 3 (Phase 3) | Jun 30, 2023 | Biotheus, Jilin Provincial Tumor Hospital |
| NCT05756972 | Phase 2/Phase 3 (Phase 3) | Jun 26, 2023 | Biotheus, Shantou University |
| NCT05879055 | Phase 2 | May 17, 2023 | Biotheus, People's Liberation Army of China |
| NCT05918107 | Phase 2 | Aug 13, 2022 | Biotheus |
| NCT05918133 | Phase 1/Phase 2 (Phase 2) | Jul 1, 2022 | Biotheus, Fudan University |
| NCT05879068 | Phase 2 | May 27, 2022 | Biotheus, Jilin Provincial Tumor Hospital |
| NCT05864105 | Phase 2 | Apr 22, 2022 | Biotheus, Chinese Academy of Medical Sciences |
| NCT05918445 | Phase 1/Phase 2 (Phase 2) | Mar 9, 2021 | Biotheus, Shanghai Oriental Hospital |
Showing 13 of 13 trials
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Organizations
Research & Development (10)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Biotheus | For profit | 12 | 12 | 2 | 2021 |
| Fudan University | Academic/Hospital | 3 | 0 | 2 | 2022 |
| Jilin Provincial Tumor Hospital | Academic/Hospital | 3 | 0 | 2 | 2022 |
| Biontech | For profit | 1 | 0 | 1 | 2025 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Huazhong University of Science and Technology | Academic/Hospital | 1 | 1 | 1 | 2025 |
| People's Liberation Army of China | Government | 1 | 0 | 1 | 2023 |
| Shanghai Oriental Hospital | Academic/Hospital | 1 | 0 | 1 | 2021 |
| Shantou University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Sun Yat-Sen University | Academic/Hospital | 1 | 0 | 1 | 2025 |
10 organizations
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