← Mechanisms of action
MUC1
SINGLE PROTEINHomo sapiens
Preferred name: Mucin-1 ChEMBL ↗
Linked proteins
Drugs acting on this target (75)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| HMFG1 | Adcc | experimental | mAb | MUC1 |
| HMFG2 | Adcc | experimental | mAb | MUC1 |
| m1231 | Antagonist | experimental | mAb | MUC1 |
| as-1403 | Binding agent | experimental | mAb | MUC1 binding agent |
| cantuzumab mertansine | Binding agent | experimental | mAb | MUC1 binding agent |
| cantuzumab ravtansine | Binding agent | experimental | mAb | MUC1 binding agent |
| clivatuzumab tetraxetan | Binding agent | experimental | mAb | MUC1 binding agent |
| cmb-401 | Binding agent | experimental | mAb | MUC1 binding agent |
| ds-3939a | Binding agent | experimental | mAb | MUC1 binding agent |
| durvalumab (imfinzi) | Binding agent | approved | mAb | Mucin-1 binding agent |
| HMFG1-Y90 | Binding agent | experimental | mAb | MUC1 |
| m170 | Binding agent | experimental | mAb | Mucin-1 binding agent |
| pemtumomab | Binding agent | experimental | mAb | MUC1 binding agent |
| sar566658 | Binding agent | experimental | mAb | MUC1 binding agent |
| sontuzumab | Binding agent | experimental | mAb | MUC1 binding agent |
| tacatuzumab tetraxetan | Binding agent | experimental | mAb | MUC1 binding agent |
| tin difluoride | Binding agent | experimental | Small molecule | MUC1 binding agent |
| anti-muc1 vaccine | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| etbx-061 | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| falimarev | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| immucin | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| muc-1 peptide vaccine | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| muc-2-klh vaccine | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| muc1 dendritic cell vaccine | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| muc1 peptide | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| muc1-gene-dc-ctl | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| muc1-klh conjugate vaccine | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| muc1-klh vaccine/qs21 | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| muc1-peptide-dc-ctl | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| mucin (theratope) | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| mva-muc1-il2 | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| rv-df3/muc1 | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| sb-as2 | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| tecemotide | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| tg4010 | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| triadeno vaccine | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| vaccinia-muc1 vaccine | Immunity, active | experimental | Vaccine | MUC1 immunity, active |
| Activated CIK with CD3-MUC1 | Immunity, passive | experimental | Cell therapy | MUC1 immunity, passive |
| anti-ctla-4/pd-1 expressing muc1-car-t cells | Immunity, passive | experimental | Cell therapy | MUC1 immunity, passive |
| autologous muc1-activated t-cells | Immunity, passive | experimental | Cell therapy | MUC1 immunity, passive |
| cl25216 | Immunity, passive | experimental | Cell therapy | MUC1 immunity, passive |
| in111 monoclonal antibody bre-3 | Immunity, passive | experimental | mAb | MUC1 immunity, passive |
| muc1 car-t cells | Immunity, passive | experimental | Cell therapy | MUC1 immunity, passive |
| muc1/cll1/cd33/cd38/cd56/cd123-specific gene-engineered t cells | Immunity, passive | experimental | Cell therapy | MUC1 immunity, passive |
| p-muc1c-allo1 car-t cells | Immunity, passive | experimental | Cell therapy | MUC1 immunity, passive |
| psca or muc1 targeting car-t cells | Immunity, passive | experimental | Cell therapy | MUC1 immunity, passive |
| tils and car-tils targeting her2, mesothelin, psca, muc1, lewis-y, gpc3, axl, egfr, claudin18.2/6, ror1, gd1, or b7-h3 | Immunity, passive | experimental | Cell therapy | MUC1 immunity, passive |
| anti-cd3-muc1 bispecific antibody | Inhibitor | experimental | mAb | MUC1 inhibitor |
| ar-20.5 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| as-1403 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| bgb-b3227 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| bm7pe | Inhibitor | experimental | mAb | MUC1 inhibitor |
| bre-3 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| cantuzumab mertansine | Inhibitor | experimental | mAb | MUC1 inhibitor |
| cantuzumab ravtansine | Inhibitor | experimental | mAb | MUC1 inhibitor |
| clivatuzumab tetraxetan | Inhibitor | experimental | mAb | MUC1 inhibitor |
| cmb-401 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| dm002 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| gatipotuzumab | Inhibitor | experimental | mAb | Mucin-1 inhibitor |
| go-203-2c | Inhibitor | experimental | Small molecule | MUC1 inhibitor |
| in111 monoclonal antibody m170 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| m0324 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| pemtumomab | Inhibitor | experimental | mAb | MUC1 inhibitor |
| r926112 | Inhibitor | experimental | Small molecule | MUC1 inhibitor |
| sar566658 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| sbo-154 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| sontuzumab | Inhibitor | experimental | mAb | MUC1 inhibitor |
| tab004 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| y90 monoclonal antibody bre-3 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| y90 monoclonal antibody m170 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| y90 monoclonal antibody m195 | Inhibitor | experimental | mAb | MUC1 inhibitor |
| ar-20.5 | Other | experimental | mAb | MUC1 other |
| sontuzumab | Other | experimental | mAb | MUC1 other |
| 90y-imp-288 | Radiodepletion | experimental | mAb | MUC1 radiodepletion |
| tecemotide | Vaccine antigen | experimental | Vaccine | Mucin-1 vaccine antigen |