muc1 car-t cells
Cell therapyexperimental
Clinical trial activity
8 trials · 8 clinical orgs · 0 marketing orgs
Phase 1
8
Phase 2
7
Phase 3
0
Phase 4
0
Earliest trial started Oct 1, 2015 (NCT02587689)
Timeline
2010s
- Jan 1, 2015
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
- Breast Neoplasms · Phase 1/Phase 2
- Carcinoma, Hepatocellular · Phase 1/Phase 2
- Carcinoma, Non-Small-Cell Lung · Phase 1/Phase 2
- Cholangiocarcinoma · Phase 1/Phase 2
- Colorectal Neoplasms · Phase 1/Phase 2
- Esophageal Neoplasms · Phase 1/Phase 2
- Fallopian Tube Neoplasms · Phase 1
- Glioma · Phase 1/Phase 2
- Lung Neoplasms · Phase 1/Phase 2
- Multiple Myeloma · Phase 1
- Ovarian Neoplasms · Phase 1
- Pancreatic Neoplasms · Phase 1/Phase 2
- Stomach Neoplasms · Phase 1/Phase 2
- Triple Negative Breast Neoplasms · Phase 1
Mechanism of action
- Mucin-1Immunity, passive
MUC1 immunity, passive
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- anti-muc1 car-pnk cells
- anti-muc1 car t cells
- anti-muc1 car-t cells
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04025216 | Phase 1 | Aug 1, 2019 | Tmunity Therapeutics |
| NCT05812326 | Phase 1/Phase 2 (Phase 2) | May 17, 2019 | Guangzhou Anjie Biomedical Technology Co., Ltd., Sun Yat-Sen University |
| NCT03706326 | Phase 1/Phase 2 (Phase 2) | Sep 28, 2018 | Guangdong Pharmaceutical University, Guangzhou Anjie Biomedical Technology Co., Ltd. |
| NCT03633773 | Phase 1/Phase 2 (Phase 2) | Jul 1, 2018 | Zhejiang University |
| NCT03525782 | Phase 1/Phase 2 (Phase 2) | Feb 1, 2018 | Guangdong Pharmaceutical University, University of Technology, Sydney |
| NCT02839954 | Phase 1/Phase 2 (Phase 2) | Jul 1, 2016 | Hefei University, PersonGen BioTherapeutics (Suzhou) Co., Ltd. |
| NCT02617134 | Phase 1/Phase 2 (Phase 2) | Nov 1, 2015 | Hefei University, PersonGen BioTherapeutics (Suzhou) Co., Ltd. |
| NCT02587689 | Phase 1/Phase 2 (Phase 2) | Oct 1, 2015 | Hefei University, PersonGen BioTherapeutics (Suzhou) Co., Ltd. |
Showing 8 of 8 trials
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Organizations
Research & Development (8)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Hefei University | Academic/Hospital | 3 | 0 | 1 | 2015 |
| PersonGen BioTherapeutics (Suzhou) Co., Ltd. | For profit | 3 | 3 | 1 | 2015 |
| Guangdong Pharmaceutical University | Academic/Hospital | 2 | 2 | 1 | 2018 |
| Guangzhou Anjie Biomedical Technology Co., Ltd. | Government | 2 | 0 | 1 | 2018 |
| Sun Yat-Sen University | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Tmunity Therapeutics | For profit | 1 | 1 | 1 | 2019 |
| University of Technology, Sydney | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Zhejiang University | Academic/Hospital | 1 | 1 | 1 | 2018 |
8 organizations
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