Gastrinoma
A GASTRIN-secreting neuroendocrine tumor of the non-beta ISLET CELLS, the GASTRIN-SECRETING CELLS. This type of tumor is primarily located in the PANCREAS or the DUODENUM. Majority of gastrinomas are malignant. They metastasize to the LIVER; LYMPH NODES; and BONE but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN 1).
Drugs by status
Approved for this indication (1)
Phase 2 trials (12)
Phase 1 trials (5)
Organizations
Organization Involved with Phase 4 Indications (2)
Organization Involved with Phase 3 Indications (1)
Organization Involved with Phase 2 Indications (14)
- Novartis
- National Institutes of Health (NIH)
- National Cancer Institute (NCI)
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Academic and Community Cancer Research United
- Eastern Cooperative Oncology Group
- ECOG-ACRIN Cancer Research Group
- Emory University
- Ohio State University
- Stanford University
- University of Southern California
- Mayo Clinic
- Hammersmith Medicines Research
- University of Texas at Houston
Organization Involved with Phase 1 Indications (1)