human placental derived stem cells
Cell therapyexperimental
Clinical trial activity
32 trials · 40 clinical orgs · 0 marketing orgs
Phase 1
19
Phase 2
12
Phase 3
3
Phase 4
0
Earliest trial started Aug 31, 2002 (NCT00130377)
Timeline
Indications
Studied for
- Acute Febrile Encephalopathy · Phase 2
- Adenoviridae Infections · Phase 1/Phase 2
- Adrenoleukodystrophy · Phase 1
- Anemia, Aplastic · Phase 1
- Anemia, Diamond-Blackfan · Phase 1
- Coronary Artery Disease · Phase 1
- Crohn Disease · Phase 2
- Cytomegalovirus Infections · Phase 1/Phase 2
- Diabetic Foot · Phase 2
- Diabetic Neuropathies · Early Phase 1
- Erectile Dysfunction · Phase 1
- Fucosidosis · Phase 1
- Gaucher Disease · Phase 1
- Head and Neck Neoplasms · Phase 1/Phase 2
- Heart Diseases · Phase 1
- Heart Failure · Phase 2/Phase 3
- Heart Failure, Diastolic · Phase 2
- Hematopoietic Stem Cell Transplantation · Phase 1
- Hepatitis B, Chronic · Phase 1/Phase 2
- Idiopathic Pulmonary Fibrosis · Phase 1
- Infarction, Middle Cerebral Artery · Phase 2
- Infarction, Posterior Cerebral Artery · Phase 2
- Intervertebral Disc Degeneration · Phase 2/Phase 3
- Intestinal Neoplasms · Phase 1
- Leukemia, Myeloid, Acute · Phase 1
- Leukodystrophy, Globoid Cell · Phase 1
- Leukodystrophy, Metachromatic · Phase 1
- Liver Cirrhosis · Phase 1
- Meningomyelocele · Phase 1/Phase 2
- Mucopolysaccharidosis I · Phase 1
- Mucopolysaccharidosis VI · Phase 1
- Myelodysplastic Syndromes · Phase 1
- Myocardial Ischemia · Phase 1
- Neoplasms · Phase 1/Phase 2
- Neuronal Ceroid-Lipofuscinoses · Phase 1
- Niemann-Pick Diseases · Phase 1
- Osteoarthritis · Phase 2
- Osteoarthritis, Knee · Phase 1/Phase 2
- Penile Induration · Phase 1
- Peripheral Arterial Disease · Phase 2
- Precursor Cell Lymphoblastic Leukemia-Lymphoma · Phase 1
- Primary Ovarian Insufficiency · Phase 1
- Radiation Oncology · Phase 1
- Recurrence · Phase 1/Phase 2
- Spinal Cord Compression · Phase 2
- Spinal Cord Injuries · Phase 3
- Stem Cells · Phase 2
- Stroke · Phase 2
- Wolman Disease · Phase 1
Mechanism of action
- Unspecified targetTissue restoration
tissue restoration
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- human placenta-derived cells
- human placental derived stem cells
- placenta derived mesenchymal stem cell
- placental matrix-derived mesenchymal stem cells
- plx-r18
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07158658 | N/A | Nov 13, 2025 | NuScience Medical Biologics, LLC, SygNola, LLC |
| NCT07061613 | N/A | Sep 2, 2025 | NuScience Medical Biologics, LLC, SygNola, LLC |
| NCT07039396 | N/A | Aug 26, 2025 | NuScience Medical Biologics, LLC, SygNola, LLC |
| NCT06671275 | Phase 1 | Jun 21, 2024 | Anhui Medical University, University of Science and Technology of China |
| NCT06096038 | Phase 1/Phase 2 (Phase 2) | Dec 31, 2023 | Bellicum Pharmaceuticals, University of North Carolina at Chapel Hill |
| NCT06296095 | Phase 1 | Aug 9, 2023 | Anhui Medical University |
| NCT06373809 | Early Phase 1 (Phase 1) | Oct 8, 2021 | government of nicaragua, Wake Forest University |
| NCT04804891 | Phase 1 | Sep 30, 2021 | Columbia University, Ossium Health, Inc. |
| NCT04652908 | Phase 1/Phase 2 (Phase 2) | Jun 21, 2021 | California Institute for Regenerative Medicine (CIRM), University of California, Davis |
| NCT04464213 | Phase 1 | Nov 1, 2020 | Capital Medical University |
| NCT04453111 | Phase 1/Phase 2 (Phase 2) | Jan 2, 2020 | Institute of Cell Therapy, Kyiv City Clinical Hospital № 6, The Institute of Traumatology and Orthopedics of NAMS of Ukraine |
| NCT03877471 | Phase 1 | Apr 3, 2019 | Chinese Academy of Medical Sciences, National Natural Science Foundation of China, Zhengzhou University |
| NCT03797040 | Phase 1 | Jan 1, 2019 | Pluristem Ltd. |
| NCT03536013 | N/A | May 3, 2018 | Polaris Spine and Neurosurgery, StimLabs |
| NCT02434965 | Phase 2 | Aug 1, 2017 | Celgene, New York Medical College |
| NCT03002519 | Phase 1 | Feb 8, 2017 | Pluristem Ltd. |
| NCT03028428 | Phase 2 | Dec 1, 2016 | Nanjing Medical University |
| NCT02923609 | Phase 2 | Jan 31, 2016 | University of Ljubljana |
| NCT07187362 | Phase 2/Phase 3 (Phase 3) | Oct 13, 2015 | Midwest Spine & Brain Institute |
| NCT01935635 | Phase 1/Phase 2 (Phase 2) | Jan 1, 2015 | Jiao Tong University, Second People's Hospital of Yunnan Province, Sun Yat-Sen University |
Showing 20 of 32 trials
Page 1 / 2
Organizations
Research & Development (40)
40 organizations
Page 1 / 2