cotadutide

Peptideexperimental

Clinical trial activity

24 trials · 8 clinical orgs · 0 marketing orgs

Phase 1
13
Phase 2
11
Phase 3
1
Phase 4
0

Earliest trial started Feb 1, 2015 (NCT02394314)

Timeline

2010s

  1. Jan 1, 2015

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2017

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)O)C(C)C)C(=O)O
Mol. weight
3728.09 g/mol
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No
Multi-specific
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • medi0382

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05668936Phase 1Jan 10, 2023AstraZeneca
NCT05517226Phase 1Sep 6, 2022AstraZeneca, Parexel
NCT05364931Phase 2/Phase 3 (Phase 3)Jul 14, 2022AstraZeneca
NCT05294458Phase 1Mar 28, 2022AstraZeneca, Quotient
NCT05437848Phase 1Feb 25, 2022AstraZeneca
NCT04515849Phase 2Aug 31, 2020AstraZeneca
NCT04208620Phase 1Jan 10, 2020AstraZeneca, MedImmune
NCT04019561Phase 2Sep 25, 2019MedImmune
NCT04091373Phase 1Sep 17, 2019MedImmune
NCT03745937Phase 2Jan 7, 2019MedImmune, Profil GmbH
NCT03596177Phase 2Sep 26, 2018MedImmune
NCT03625778Phase 1Aug 14, 2018MedImmune
NCT03645421Phase 2Aug 10, 2018AstraZeneca
NCT03550378Phase 2Jun 29, 2018MedImmune
NCT03555994Phase 2May 31, 2018Clinical Trial Consultants AB, Maastricht University, MedImmune
NCT03444584Phase 2May 8, 2018MedImmune
NCT03385369Phase 1Jan 5, 2018Anaheim Clinical Trials, MedImmune
NCT03341013Phase 1Nov 30, 2017MedImmune
NCT03347968Phase 1Nov 27, 2017MedImmune
NCT03235375Phase 1Oct 27, 2017MedImmune
Showing 20 of 24 trials
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Organizations

Research & Development (8)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
MedImmuneFor profit171522015
AstraZenecaFor profit9932017
Profil GmbHFor profit2012017
Anaheim Clinical TrialsFor profit1012018
Clinical Trial Consultants ABFor profit1012018
Maastricht UniversityAcademic/Hospital1012018
ParexelFor profit1012022
QuotientFor profit1012022
8 organizations
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