orageston
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Mechanism of action
- Progesterone receptorAGONIST
PGR agonist
Allylestrenol has the same function as Progesterone, it prepares the uterus for receiving the fertilised ovum and suppresses uterine motility. Progesterone binds to the progesterone and estrogen receptors. Once bound to the receptor, it will slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone) surge.
- Estrogen receptorAGONIST
Estrogen receptor agonist
Allylestrenol has the same function as Progesterone, it prepares the uterus for receiving the fertilised ovum and suppresses uterine motility. Progesterone binds to the progesterone and estrogen receptors. Once bound to the receptor, it will slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone) surge.
Chemistry & pharmacology
SMILES
C=CC[C@]1(O)CC[C@H]2[C@@H]3CCC4=CCCCC4[C@H]3CC[C@@]21C- Mol. weight
- 300.49 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3185133 ↗
- ChEMBLCHEMBL2105618 ↗
Also known as
- 17α-allylestr-4-en-17β-ol
- 17α-allylestr-4-en-17β-ol
- 3-deketo-17α-allyl-19-nortestosterone
- 3-deketo-17α-allyl-19-nortestosterone
- allylestrenol
- allylestrenol
- allylestrenol
- allylestrenol
- allylestrenol
- allylestrenol
- allylestrenol
- allyl estrenol
- allyl estrenol
- allyloestrenol
- allyloestrenol
- allyloestrenol
- gestanin
- gestanin
- gestanin
- gestanol
- gestanon
- orageston