tramazoline hydrochloride
Small moleculeexperimental
Tramazoline is a chemical that is used in the form of tramazoline hydrochloride in nasal decongestant preparations. It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus. — Wikipedia
Clinical trial activity
2 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Apr 1, 2010 (NCT01601509)
Timeline
2020s
- Jan 1, 2025
Earliest Phase 1 Sponsor(trial)
Mechanism of action
Chemistry & pharmacology
Loading structure…
SMILES
c1cc2c(c(NC3=NCCN3)c1)CCCC2- Mol. weight
- 215.3 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- Yes
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL32573 ↗
- WikipediaTramazoline ↗
- ChEMBLCHEMBL2107640 ↗
Also known as
- 2-(5,6,7,8-tetrahydro-1-naphthylamino)-2-imidazoline
- 4,5-dihydro-n-(5,6,7,8- tetrahydro-1-naphthalenyl)-1h-imidazol-2-amine
- biciron
- bisolnasal
- ellatun
- kb 227
- rhinol
- rhinospray
- spray-tish
- tramazoline
- tramazoline
- tramazoline
- tramazoline
- tramazoline
- tramazoline
- tramazoline hcl
- tramazoline hydrochloride
- tramazoline hydrochloride
- tramazoline hydrochloride
- tramazoline hydrochloride
- tramazoline hydrochloride
- tramazoline monohydrochloride
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07280663 | Early Phase 1 (Phase 1) | Oct 9, 2025 | Shanxi Medical University |
| NCT01601509 | N/A | Apr 1, 2010 | University of Athens |
Showing 2 of 2 trials
Page 1 / 1
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Shanxi Medical University | Academic/Hospital | 1 | 1 | 1 | 2025 |
| University of Athens | Academic/Hospital | 1 | 1 | 1 | 2010 |
2 organizations
Page 1 / 1