← Mechanisms of action
PDE5A
SINGLE PROTEINHomo sapiens
Preferred name: Phosphodiesterase 5A ChEMBL ↗
Linked proteins
Drugs acting on this target (16)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| avanafil (stendra) | Inhibitor | approved | Small molecule | PDE5A inhibitor |
| fadanafil | Inhibitor | experimental | Small molecule | PDE5A inhibitor |
| gisadenafil | Inhibitor | experimental | Small molecule | Phosphodiesterase 5A inhibitor |
| hgp1201 | Inhibitor | experimental | Small molecule | PDE5A inhibitor |
| ibudilast | Inhibitor | experimental | Small molecule | Phosphodiesterase 5A inhibitor |
| lodenafil | Inhibitor | experimental | Small molecule | PDE5A inhibitor |
| Mirodenafil | Inhibitor | experimental | Small molecule | PDE5A inhibitor |
| pf-00489791 | Inhibitor | experimental | Small molecule | Phosphodiesterase 5A inhibitor |
| pf-00592379 | Inhibitor | experimental | Small molecule | PDE5A inhibitor |
| pf-03049423 | Inhibitor | experimental | Small molecule | PDE5A inhibitor |
| sildenafil (viagra) | Inhibitor | approved | Small molecule | PDE5A inhibitor |
| slx-2101 | Inhibitor | experimental | Small molecule | PDE5A inhibitor |
| tadalafil (cialis) | Inhibitor | approved | Small molecule | PDE5A inhibitor |
| tpn171h | Inhibitor | experimental | Small molecule | PDE5A inhibitor |
| udenafil | Inhibitor | experimental | Small molecule | PDE5A inhibitor |
| vardenafil (levitra) | Inhibitor | approved | Small molecule | PDE5A inhibitor |