CDEK
← Mechanisms of action

CHRNA7

SINGLE PROTEINHomo sapiens
Preferred name: Neuronal acetylcholine receptor protein alpha-7 subunit ChEMBL ↗

Linked proteins

Drugs acting on this target (24)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
3-2,4 dimethoxybenzylideneActivatorexperimentalSmall moleculeCHRNA7 activator
nornicotineActivatorexperimentalSmall moleculeCHRNA7 activator
abt-126AgonistexperimentalSmall moleculeCHRNA7 agonist
abt107AgonistexperimentalSmall moleculeCHRNA7 agonist
azd-0328AgonistexperimentalSmall moleculeCHRNA7 agonist
bradaniclineAgonistexperimentalSmall moleculeCHRNA7 agonist
gts-21AgonistexperimentalSmall moleculeNeuronal acetylcholine receptor protein alpha-7 subunit agonist
nd0801AgonistexperimentalSmall moleculeCHRNA7 agonist
palopegteriparatide (Yorvipath)AgonistapprovedPeptideCHRNA7 agonist
pha543613AgonistexperimentalSmall moleculeCHRNA7 agonist
tc-6987AgonistexperimentalSmall moleculeCHRNA7 agonist
[18f]asemAntagonistexperimentalSmall moleculeCHRNA7 antagonist
bnc210InhibitorexperimentalSmall moleculeCHRNA7 inhibitor
n6022InhibitorexperimentalSmall moleculeCHRNA7 inhibitor
asm-024ModulatorexperimentalSmall moleculeCHRNA7 modulator
apn-1125Partial agonistexperimentalSmall moleculeCHRNA7 partial agonist
aqw051Partial agonistexperimentalSmall moleculeCHRNA7 partial agonist
bms-933043Partial agonistexperimentalSmall moleculeCHRNA7 partial agonist
enceniclinePartial agonistexperimentalSmall moleculeCHRNA7 partial agonist
gts-21Partial agonistexperimentalSmall moleculeCHRNA7 partial agonist
rg3487Partial agonistexperimentalSmall moleculeCHRNA7 partial agonist
ssr-180711Partial agonistexperimentalSmall moleculeCHRNA7 partial agonist
anvylic-3288Positive allosteric modulatorexperimentalSmall moleculeCHRNA7 positive allosteric modulator
jnj-39393406Positive allosteric modulatorexperimentalSmall moleculeCHRNA7 positive allosteric modulator