← Mechanisms of action
PARP2
SINGLE PROTEINHomo sapiens
Preferred name: Poly [ADP-ribose] polymerase 2 ChEMBL ↗
Linked proteins
Drugs acting on this target (11)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| 2x-121 | Inhibitor | experimental | Small molecule | Poly [ADP-ribose] polymerase 2 inhibitor |
| abt-767 | Inhibitor | experimental | Small molecule | PARP2 inhibitor |
| cep-9722 | Inhibitor | experimental | Small molecule | PARP2 inhibitor |
| fluzoparil | Inhibitor | experimental | Small molecule | PARP2 inhibitor |
| jpi-547 | Inhibitor | experimental | Small molecule | PARP2 inhibitor |
| niraparib (zejula) | Inhibitor | approved | Small molecule | PARP2 inhibitor |
| pamiparib | Inhibitor | experimental | Small molecule | Poly [ADP-ribose] polymerase 2 inhibitor |
| sc10914 | Inhibitor | experimental | Small molecule | PARP2 inhibitor |
| Senaparib | Inhibitor | experimental | Small molecule | Poly [ADP-ribose] polymerase 2 inhibitor |
| simmiparib | Inhibitor | experimental | Small molecule | PARP2 inhibitor |
| talazoparib (talzenna) | Inhibitor | approved | Small molecule | PARP2 inhibitor |