← Mechanisms of action
PARP 1, 2 and 3
PROTEIN FAMILYHomo sapiens
Linked proteins
Drugs acting on this target (6)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| nicotinamide | Antagonist | approved | Small molecule | PARP 1, 2 and 3 antagonist |
| iniparib | Inhibitor | experimental | Small molecule | PARP 1, 2 and 3 inhibitor |
| niraparib (zejula) | Inhibitor | approved | Small molecule | PARP 1, 2 and 3 inhibitor |
| olaparib (lynparza) | Inhibitor | approved | Small molecule | PARP 1, 2 and 3 inhibitor |
| rucaparib (rubraca) | Inhibitor | approved | Small molecule | PARP 1, 2 and 3 inhibitor |
| veliparib | Inhibitor | experimental | Small molecule | PARP 1, 2 and 3 inhibitor |