cep-9722
Small moleculeexperimental
Clinical trial activity
3 trials · 1 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Jun 1, 2009 (NCT00920595)
Timeline
2000s
- Jan 1, 2009
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
Mechanism of action
- Poly [ADP-ribose] polymerase 10INHIBITOR
PARP10 inhibitor
- Poly [ADP-ribose] polymerase 2INHIBITOR
PARP2 inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
COc1cccc2[nH]c3c4c(c5c(c3c12)C(=O)N(CN1CCN(C)CC1)C5=O)CCC4- Mol. weight
- 418.5 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4297461 ↗
Also known as
- cep-9722
- cep-9722
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01311713 | Phase 1/Phase 2 (Phase 2) | May 1, 2011 | Cephalon |
| NCT01345357 | Phase 1 | May 1, 2011 | Cephalon |
| NCT00920595 | Phase 1 | Jun 1, 2009 | Cephalon |
Showing 3 of 3 trials
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Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Cephalon | For profit | 3 | 3 | 2 | 2009 |
1 organizations
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