← Mechanisms of action
SLC5A2
SINGLE PROTEINHomo sapiens
Preferred name: Sodium/glucose cotransporter 2 ChEMBL ↗
Linked proteins
Drugs acting on this target (26)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| canagliflozin (invokana) | Antagonist | approved | Small molecule | SGLT2 |
| jp-2266 | Antagonist | experimental | Small molecule | SGLT2 |
| rongliflozin | Antagonist | experimental | Small molecule | SGLT2 |
| isis 388626 | Antisense inhibitor | experimental | Nucleic acid | SLC5A2 antisense inhibitor |
| abp1011t | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| ave2268 | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| bexagliflozin (Brenzavvy) | Inhibitor | approved | Small molecule | SLC5A2 inhibitor |
| bi 44847 | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| canagliflozin (invokana) | Inhibitor | approved | Small molecule | SLC5A2 inhibitor |
| ckd-382 | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| da-5221 | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| dapagliflozin (farxiga) | Inhibitor | approved | Small molecule | SLC5A2 inhibitor |
| egt0001474 | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| empagliflozin (jardiance) | Inhibitor | approved | Small molecule | SLC5A2 inhibitor |
| enavogliflozin | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| ertugliflozin (Steglatro) | Inhibitor | approved | Small molecule | SLC5A2 inhibitor |
| gsk1614235 | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| henagliflozin | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| ipragliflozin (sublet) | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| licogliflozin | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| remogliflozin etabonate | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| rmjh-111b | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| Sergliflozin | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| sotagliflozin (Inpefa) | Inhibitor | approved | Small molecule | SLC5A2 inhibitor |
| tofogliflozin hydrate | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |
| yg1699 | Inhibitor | experimental | Small molecule | SLC5A2 inhibitor |