← Mechanisms of action
F9
SINGLE PROTEINHomo sapiens
Preferred name: Coagulation factor IX ChEMBL ↗
Linked proteins
Drugs acting on this target (39)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| vgb-r04 | Activator | experimental | Gene therapy | F9 activator |
| anivamersen | Agonist | experimental | Nucleic acid | F9 agonist |
| coagulation factor ix (Recombinant), Fc-fusion protein (Alprolix) | Agonist | approved | Biological | F9 agonist |
| factor ix albumin fusion protein (Idelvion) | Agonist | approved | Recombinant protein | F9 agonist |
| human coagulation factor ix (Mononine) | Agonist | approved | Recombinant protein | F9 agonist |
| mim8 | Agonist | experimental | mAb | F9 agonist |
| fidanacogene elaparvovec | Exogenous gene | experimental | Gene therapy | Coagulation factor IX exogenous gene |
| albutrepenonacog alfa | Exogenous protein | experimental | Recombinant protein | Coagulation factor IX exogenous protein |
| coagulation factor ix (Recombinant) (Rixubis) | Exogenous protein | approved | Recombinant protein | Coagulation factor IX exogenous protein |
| etranacogene dezaparvovec (Hemgenix) | Exogenous protein | approved | Gene therapy | Coagulation factor IX exogenous protein |
| human coagulation factor ix (Mononine) | Exogenous protein | approved | Recombinant protein | Coagulation factor IX exogenous protein |
| human factor ix complex (prothrombin complex concentrate) (Bebulin) | Exogenous protein | approved | Biological | Coagulation factor IX exogenous protein |
| nonacog beta pegol | Exogenous protein | experimental | Biological | Coagulation factor IX exogenous protein |
| valoctocogene roxaparvovec (Roctavian) | Exogenous protein | approved | Gene therapy | Coagulation factor IX exogenous protein |
| nxt007 | Inhibitor | experimental | mAb | F9 inhibitor |
| pegnivacogin | Inhibitor | experimental | Nucleic acid | F9 inhibitor |
| ss109 | Inhibitor | experimental | Small molecule | F9 inhibitor |
| ttp889 | Inhibitor | experimental | Small molecule | F9 inhibitor |
| ulinastatin | Inhibitor | experimental | Recombinant protein | F9 inhibitor |
| anb-002 | Modulator | experimental | Recombinant protein | F9 modulator |
| etranacogene dezaparvovec (Hemgenix) | Other | approved | Gene therapy | F9 other |
| aav5-hfix | Supplementation | experimental | Gene therapy | F9 supplementation |
| aav8-hfix19 | Supplementation | experimental | Gene therapy | F9 supplementation |
| aavrh10fix | Supplementation | experimental | Gene therapy | F9 supplementation |
| adeno-associated viral with human factor ix | Supplementation | experimental | Gene therapy | F9 supplementation |
| albutrepenonacog alfa | Supplementation | experimental | Recombinant protein | F9 supplementation |
| bbm-h901 | Supplementation | experimental | Gene therapy | F9 supplementation |
| be-101 | Supplementation | experimental | Gene therapy | F9 supplementation |
| coagulation factor ix (Recombinant) (Rixubis) | Supplementation | approved | Recombinant protein | F9 supplementation |
| fidanacogene elaparvovec (BEQVEZ) | Supplementation | approved | Gene therapy | F9 supplementation |
| fidanacogene elaparvovec | Supplementation | experimental | Gene therapy | F9 supplementation |
| isu304 | Supplementation | experimental | Recombinant protein | F9 supplementation |
| lnp1265 | Supplementation | experimental | Gene therapy | F9 supplementation |
| nonacog beta pegol | Supplementation | experimental | Biological | F9 supplementation |
| pegnivacogin | Supplementation | experimental | Nucleic acid | F9 supplementation |
| regv131 | Supplementation | experimental | Gene therapy | F9 supplementation |
| scaav2/8-lp1-hfixco | Supplementation | experimental | Gene therapy | F9 supplementation |
| verbrinacogene setparvovec | Supplementation | experimental | Gene therapy | F9 supplementation |
| yuva-gt-f901 | Supplementation | experimental | Gene therapy | F9 supplementation |