← Mechanisms of action
SIGMAR1
SINGLE PROTEINHomo sapiens
Preferred name: Sigma opioid receptor ChEMBL ↗
Linked proteins
Drugs acting on this target (9)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| blarcamesine | Agonist | experimental | Small molecule | SIGMAR1 agonist |
| dextromethorphan (delsym) | Agonist | approved | Small molecule | SIGMAR1 agonist |
| opipramol (Insidon) | Agonist | experimental | Small molecule | SIGMAR1 agonist |
| pentoxiverine | Agonist | experimental | Small molecule | SIGMAR1 agonist |
| fenfluramine (Pondimin) | Antagonist | approved | Small molecule | SIGMAR1 antagonist |
| xc130-a10h | Antagonist | experimental | Small molecule | SIGMAR1 antagonist |
| anavex3-71 | Inhibitor | experimental | Small molecule | SIGMAR1 inhibitor |
| deuterated dextromethorphan | Inhibitor | experimental | Small molecule | SIGMAR1 inhibitor |
| pentazocine (talwin) | Modulator | approved | Small molecule | SIGMAR1 modulator |