blarcamesine
Small moleculeexperimental
Clinical trial activity
9 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
6
Phase 3
3
Phase 4
0
Earliest trial started Dec 1, 2014 (NCT02244541)
Timeline
2010s
- Jan 1, 2014
Earliest Phase 2 Sponsor(trial)
Indications
Mechanism of action
- Sigma opioid receptorAGONIST
SIGMAR1 agonist
Chemistry & pharmacology
Loading structure…
SMILES
CN(C)CC1CCOC1(c1ccccc1)c1ccccc1- Mol. weight
- 281.4 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4297224 ↗
Also known as
- anavex2-73
- anavex2-73
- anavex2-73
- tetrahydro-n, n-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04304482 | Phase 2/Phase 3 (Phase 3) | Apr 30, 2020 | Anavex Life Sciences Corp. |
| NCT04575259 | Phase 2 | Oct 10, 2019 | Anavex Life Sciences Corp. |
| NCT04314934 | Phase 2/Phase 3 (Phase 3) | Oct 10, 2019 | Anavex Life Sciences Corp. |
| NCT03941444 | Phase 2 | May 6, 2019 | Anavex Life Sciences Corp. |
| NCT03758924 | Phase 2 | Feb 28, 2019 | Anavex Life Sciences Corp., Emory University, International Rett Syndrome Foundation |
| NCT03774459 | Phase 2 | Jul 9, 2018 | Anavex Life Sciences Corp. |
| NCT03790709 | Phase 2/Phase 3 (Phase 3) | Jul 3, 2018 | Anavex Life Sciences Corp. |
| NCT02756858 | Phase 2 | Mar 1, 2016 | Anavex Life Sciences Corp. |
| NCT02244541 | Phase 2 | Dec 1, 2014 | Anavex Life Sciences Corp., Caulfield Hospital |
Showing 9 of 9 trials
Page 1 / 1
Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Anavex Life Sciences Corp. | For profit | 9 | 9 | 2 | 2014 |
| Caulfield Hospital | Academic/Hospital | 1 | 0 | 1 | 2014 |
| Emory University | Academic/Hospital | 1 | 0 | 1 | 2019 |
| International Rett Syndrome Foundation | Academic/Hospital | 1 | 0 | 1 | 2019 |
4 organizations
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