opipramol
Trade name: Insidon
Homeopathy or homoeopathy is a pseudoscientific system of alternative medicine. It was conceived in 1796 by the German physician Samuel Hahnemann. Its practitioners, called homeopaths or homeopathic physicians, believe that a substance that causes symptoms of a disease in healthy people can cure similar symptoms in sick people; this doctrine is called similia similibus curentur, or "like cures like". Homeopathic preparations are termed remedies and are made using homeopathic dilution. In this process, the selected substance is repeatedly diluted until the final product is chemically indistinguishable from the diluent. Often not even a single molecule of the original substance can be expected to remain in the product. Between each dilution homeopaths may hit and/or shake the product, claiming this makes the diluent "remember" the original substance after its removal. Practitioners claim that such preparations, upon oral intake, can treat or cure disease. — Wikipedia
Clinical trial activity
6 trials · 4 clinical orgs · 1 marketing orgs
Earliest trial started Jul 28, 2010 (NCT05605938)
Timeline
Indications
Approved for
Mechanism of action
- Sigma opioid receptorAGONIST
SIGMAR1 agonist
Chemistry & pharmacology
SMILES
OCCN1CCN(CCCN2c3ccccc3C=Cc3ccccc32)CC1- Mol. weight
- 363.5 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaHomeopathy ↗
- ChEMBLCHEMBL370753 ↗
- WikipediaOpipramol ↗
Also known as
- opipramol
- opipramol
- opipramol
- opipramol
- opipramol
- opipramol
- opipramol dihydrochloride
- opipramol dihydrochloride
- opipramol dihydrochloride
- opipramol dihydrochloride
- opipramol dihydrochloride
- opramidol
- tenoten
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03065998 | Early Phase 1 (Phase 1) | Mar 1, 2017 | Bar Ilan University, Government of Israel |
| NCT03036293 | Phase 4 | Feb 8, 2017 | Materia Medica Holding |
| NCT03159611 | Phase 3 | Feb 19, 2016 | Materia Medica Holding |
| NCT03159104 | Phase 3 | Aug 25, 2015 | Materia Medica Holding |
| NCT02374567 | Phase 3 | Jan 1, 2015 | Gottfried Wilhelm Leibniz Universität Hannover |
| NCT05605938 | Phase 4 | Jul 28, 2010 | Materia Medica Holding |
Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Materia Medica Holding | For profit | 4 | 4 | 2 | 2010 |
| Bar Ilan University | Academic/Hospital | 1 | 0 | 1 | 2017 |
| Gottfried Wilhelm Leibniz Universität Hannover | Academic/Hospital | 1 | 1 | 1 | 2015 |
| Government of Israel | Government | 1 | 1 | 1 | 2017 |
Marketing (1)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Geigy | For profit | NDA | Jun 1, 1961 |