opipramol

Trade name: Insidon

Small moleculeexperimental

Homeopathy or homoeopathy is a pseudoscientific system of alternative medicine. It was conceived in 1796 by the German physician Samuel Hahnemann. Its practitioners, called homeopaths or homeopathic physicians, believe that a substance that causes symptoms of a disease in healthy people can cure similar symptoms in sick people; this doctrine is called similia similibus curentur, or "like cures like". Homeopathic preparations are termed remedies and are made using homeopathic dilution. In this process, the selected substance is repeatedly diluted until the final product is chemically indistinguishable from the diluent. Often not even a single molecule of the original substance can be expected to remain in the product. Between each dilution homeopaths may hit and/or shake the product, claiming this makes the diluent "remember" the original substance after its removal. Practitioners claim that such preparations, upon oral intake, can treat or cure disease. — Wikipedia

Clinical trial activity

6 trials · 4 clinical orgs · 1 marketing orgs

Phase 1
1
Phase 2
3
Phase 3
3
Phase 4
2

Earliest trial started Jul 28, 2010 (NCT05605938)

Timeline

1960s

  1. Jun 1, 1961

    Geigy — First NDA Organization

  2. Jun 1, 1961

    Geigy — NDA Organization

2010s

  1. Jan 1, 2015

    Earliest Phase 3 Sponsor(trial)

  2. Jan 1, 2017

    Earliest Phase 1 Sponsor(trial)

Indications

Approved for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

OCCN1CCN(CCCN2c3ccccc3C=Cc3ccccc32)CC1
Mol. weight
363.5 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • opipramol
  • opipramol
  • opipramol
  • opipramol
  • opipramol
  • opipramol
  • opipramol dihydrochloride
  • opipramol dihydrochloride
  • opipramol dihydrochloride
  • opipramol dihydrochloride
  • opipramol dihydrochloride
  • opramidol
  • tenoten

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT03065998Early Phase 1 (Phase 1)Mar 1, 2017Bar Ilan University, Government of Israel
NCT03036293Phase 4Feb 8, 2017Materia Medica Holding
NCT03159611Phase 3Feb 19, 2016Materia Medica Holding
NCT03159104Phase 3Aug 25, 2015Materia Medica Holding
NCT02374567Phase 3Jan 1, 2015Gottfried Wilhelm Leibniz Universität Hannover
NCT05605938Phase 4Jul 28, 2010Materia Medica Holding
Showing 6 of 6 trials
Page 1 / 1

Organizations

Research & Development (4)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Materia Medica HoldingFor profit4422010
Bar Ilan UniversityAcademic/Hospital1012017
Gottfried Wilhelm Leibniz Universität HannoverAcademic/Hospital1112015
Government of IsraelGovernment1112017
4 organizations
Page 1 / 1

Marketing (1)

OrganizationOrg typeRelationshipDate
GeigyFor profitNDAJun 1, 1961