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Highest phase reached
Phase 4
First clinical trial
Aug 27, 2013First marketed drug
Jul 20, 2018First NDA
Jul 20, 2018Last known activity
Mar 31, 2026
Acquired by Servier on Dec 21, 2020
Timeline
2000s
- Jul 1, 2007
Agios Pharmaceuticals, Inc.— Founded
2010s
- Jul 20, 2018
ivosidenib— NDA Organization
- Jul 20, 2018
ivosidenib— NDA Secondary Org
Drugs by trial phase (29 distinct, 62 trials)
Phase 4 (1 own, 0 via acquisition)
Phase 3 (3 own, 0 via acquisition)
Phase 2 (5 own, 0 via acquisition)
Phase 1 (20 own, 0 via acquisition)
Indications
Approved for
Studied for
- Anemia, Hemolytic
- Anemia, Hemolytic, Congenital Nonspherocytic
- Anemia, Sickle Cell
- Cholangiocarcinoma
- Chondrosarcoma
- Glioma
- Hematologic Diseases
- Hematologic Neoplasms
- Immunoblastic Lymphadenopathy
- Leukemia
- Leukemia, Myeloid
- Leukemia, Myeloid, Acute
- Liver Diseases
- Lymphoma
- Lymphoma, T-Cell
- Myelodysplastic Syndromes
- Myeloproliferative Disorders
- Neoplasms
- Preleukemia
- Pyruvate Metabolism, Inborn Errors
- Syndrome
- Thalassemia
Marketed drugs (2)
Recent trials (50)
- NCT03245424Lead sponsorN/A—
- NCT07241234Lead sponsorPhase 1Mar 31, 2026
- NCT07075640Lead sponsorPhase 1Jul 7, 2025
- NCT07055243CollaboratorPhase 2Jun 26, 2025
- NCT06924970Lead sponsorPhase 2May 1, 2025
- NCT06745271Lead sponsorPhase 1Dec 20, 2024
- NCT06286046Lead sponsorPhase 2Nov 30, 2024
- NCT06286046OfficialPhase 2Nov 30, 2024
- NCT06648824Lead sponsorPhase 1Oct 31, 2024
- NCT06648824OfficialPhase 1Oct 31, 2024
- NCT06286033Lead sponsorPhase 1Feb 20, 2024
- NCT05777993Lead sponsorPhase 4Jul 5, 2023
- NCT05610657Lead sponsorPhase 1Dec 31, 2022
- NCT05490446Lead sponsorPhase 2Oct 20, 2022
- NCT05490446Study chairPhase 2Oct 20, 2022
Details
- Founded
- Cambridge, MA, US Jul 1, 2007
- First NDA
- Jul 20, 2018
- Last known activity
- Mar 31, 2026
Designations held
- Orphan drug
- Fast track
- Priority review