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Intercellular Signaling Peptides and Proteins
Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.
Subtype terms (34)
More specific conditions that are subtypes of Intercellular Signaling Peptides and Proteins in the MeSH hierarchy.
- Adipokines
- Agouti-Related Protein
- Agouti Signaling Protein
- Angiogenic Proteins
- Apelin
- B7 Antigens
- CCN Intercellular Signaling Proteins
- Cytokines
21 drugs (16 approved, 5 experimental)
- EGF Family of Proteins
- Endothelial Growth Factors
- Endothelins
2 drugs experimental
- Ephrins
- Fibroblast Growth Factors
4 drugs (1 approved, 3 experimental)
- Growth Arrest-Specific Protein 6
- Hedgehog Proteins
4 drugs (3 approved, 1 experimental)
- Insulin-Like Peptides
- Kinins
- Kisspeptins
- Matrix Metalloproteinases, Secreted
- Midkine
- Myocilin
- Myokines
- Nerve Growth Factors
- Noggin Protein
- Parathyroid Hormone-Related Protein
- Platelet-Derived Growth Factor
2 drugs (1 approved, 1 experimental)
- Progranulins
- Semaphorins
- Serrate-Jagged Proteins
- Slit Homolog 2 Protein
- TGF-beta Superfamily Proteins
- Tolloid-Like Metalloproteinases
- Transforming Growth Factors
- Wnt Proteins
Drugs by status
Phase 1 trials (4)