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HIV-1

The type species of LENTIVIRUS and the etiologic agent of AIDS. It is characterized by its cytopathic effect and affinity for the T4-lymphocyte.

Drugs by status

Approved for this indication (2)

  • rilpivirine
  • lenacapavir

Phase 4 trials (18)

  • efavirenz
  • abacavir
  • dolutegravir
  • tenofovir
  • ritonavir
  • lamivudine
  • nevirapine
  • atazanavir
  • lopinavir
  • fosamprenavir
  • emtricitabine
  • darunavir
  • zidovudine
  • bictegravir
  • raltegravir
  • tenofovir alafenamide
  • cobicistat
  • elvitegravir

Phase 3 trials (4)

  • maraviroc
  • doravirine
  • etravirine
  • islatravir

Phase 2 trials (8)

  • dapivirine
  • enfuvirtide
  • lersivirine
  • tmc310911
  • ad26.mos.hiv
  • clade c gp140
  • mva.hiva
  • autologous cd34+ hematopoietic progenitor cells transduced with anti-hiv-1 ribozyme

Phase 1 trials (24)

  • 3bnc117
  • mva.hivconsv
  • pgt121
  • aluminum hydroxide
  • abbv-181
  • hiv dna vaccine
  • mrkad5
  • mym-v101
  • trivalent mrkad5 hiv-1 gag/pol/nef
  • v520
  • vrc-hivadv027-00-vp
  • vrc-hivadv038-00-vp
  • vrc-hivmab080-00-ab
  • sodium chloride
  • simeprevir
  • vrc07-523ls
  • mgd014
  • ch505w100
  • 3m-052-af
  • HIV-1 car-t cell, third generation
  • mgd020
  • cl-197
  • mk-8510
  • cmv/hiv-car t cells

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The Clinical Drug Experience Knowledgebase — tracking drugs, sponsoring organizations, and clinical trials from first-in-human testing through approval.

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