vrc-hivmab080-00-ab
mAbexperimental
Clinical trial activity
25 trials · 29 clinical orgs · 0 marketing orgs
Phase 1
22
Phase 2
6
Phase 3
0
Phase 4
0
Earliest trial started Apr 1, 2015 (NCT02256631)
Timeline
Indications
Mechanism of action
- T-cell surface antigen CD4BINDING AGENT
T-cell surface antigen CD4 binding agent
- Human immunodeficiency virusImmunity, passive
Human immunodeficiency virus immunity, passive
Chemistry & pharmacology
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4298127 ↗
Also known as
- 10-1074
- 10-1074-ls
- vrc-hivmab080-00-ab
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06205602 | Phase 2 | Oct 15, 2024 | National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT06031272 | Phase 1 | Dec 4, 2023 | AIDS Clinical Trials Group, National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT05612178 | Phase 1 | Dec 29, 2022 | National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT05245292 | Phase 1 | Dec 15, 2022 | Cornell University, National Institute of Allergy and Infectious Diseases (NIAID), Rockefeller University, University of Pennsylvania |
| NCT05079451 | Phase 1 | Nov 1, 2021 | National Institute of Allergy and Infectious Diseases (NIAID), Rockefeller University, University of Pennsylvania |
| NCT04340596 | Phase 1 | Jul 1, 2020 | Cornell University, ImmunityBio, Inc., National Institute of Allergy and Infectious Diseases (NIAID), Rockefeller University |
| NCT04319367 | Phase 2 | May 31, 2020 | Bill and Melinda Gates Foundation, Imperial College London, Rockefeller University, University of Oxford |
| NCT04250636 | Phase 1 | Feb 28, 2020 | Cornell University, National Institute of Allergy and Infectious Diseases (NIAID), Rockefeller University, University of Pennsylvania |
| NCT04173819 | Phase 1/Phase 2 (Phase 2) | Dec 1, 2019 | International AIDS Vaccine Initiative, Rockefeller University, University of Washington |
| NCT03928821 | Phase 1 | Jun 30, 2019 | Columbia University, National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT03837756 | Phase 2 | May 6, 2019 | Aalborg University, Aarhus University, The Peter Doherty Institute, University of Copenhagen, University of Southern Denmark, University of Utah |
| NCT03831945 | Phase 1 | Apr 4, 2019 | National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT03707977 | Phase 1/Phase 2 (Phase 2) | Mar 31, 2019 | Harvard University, National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT03619278 | Phase 1/Phase 2 (Phase 2) | Nov 1, 2018 | Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona |
| NCT03571204 | Phase 1 | Sep 10, 2018 | National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT03588715 | Phase 1 | Aug 1, 2018 | Merck, National Institute of Allergy and Infectious Diseases (NIAID), Philadelphia Fight, Rockefeller University, The Wistar Institute, University of Pennsylvania |
| NCT03554408 | Phase 1 | Jun 30, 2018 | Rockefeller University |
| NCT03526848 | Phase 1 | Jun 5, 2018 | National Institute of Allergy and Infectious Diseases (NIAID), Ragon Institute of MGH, MIT and Harvard, Rockefeller University, Yeshiva University |
| NCT02797171 | Phase 1 | Mar 1, 2017 | Desmond Tutu HIV Centre, National Institute of Allergy and Infectious Diseases (NIAID), University of Washington |
| NCT02840474 | Phase 1 | Jul 11, 2016 | National Institute of Allergy and Infectious Diseases (NIAID) |
Showing 20 of 25 trials
Page 1 / 2
Organizations
Research & Development (29)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Institute of Allergy and Infectious Diseases (NIAID) | Government | 17 | 13 | 2 | 2015 |
| Rockefeller University | Academic/Hospital | 12 | 7 | 2 | 2015 |
| University of Pennsylvania | Academic/Hospital | 4 | 0 | 1 | 2018 |
| Cornell University | Academic/Hospital | 3 | 0 | 1 | 2020 |
| University of Cologne | Academic/Hospital | 2 | 0 | 1 | 2015 |
| University of Washington | Academic/Hospital | 2 | 0 | 2 | 2017 |
| Aalborg University | Academic/Hospital | 1 | 0 | 1 | 2019 |
| Aarhus University | Academic/Hospital | 1 | 1 | 1 | 2019 |
| AIDS Clinical Trials Group | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Bill and Melinda Gates Foundation | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Columbia University | Academic/Hospital | 1 | 0 | 1 | 2019 |
| Desmond Tutu HIV Centre | Academic/Hospital | 1 | 0 | 1 | 2017 |
| Duke University | Academic/Hospital | 1 | 0 | 1 | 2015 |
| Harvard University | Academic/Hospital | 1 | 0 | 1 | 2019 |
| ImmunityBio, Inc. | For profit | 1 | 0 | 1 | 2020 |
| Imperial College London | Academic/Hospital | 1 | 1 | 1 | 2020 |
| Institut d'Investigacions Biomèdiques August Pi i Sunyer | Academic/Hospital | 1 | 0 | 1 | 2018 |
| International AIDS Vaccine Initiative | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Merck | For profit | 1 | 0 | 1 | 2018 |
| Philadelphia Fight | Academic/Hospital | 1 | 0 | 1 | 2018 |
29 organizations
Page 1 / 2