3bnc117
mAbexperimental
Clinical trial activity
30 trials · 34 clinical orgs · 0 marketing orgs
Phase 1
19
Phase 2
14
Phase 3
0
Phase 4
0
Earliest trial started Jan 1, 2014 (NCT02018510)
Timeline
Indications
Mechanism of action
- GP41INHIBITOR
HIV1 ENV inhibitor
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL5095294 ↗
Also known as
- 3bnc117
- 3bnc117-ls
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07054931 | Phase 2 | Sep 5, 2025 | University of Oxford |
| NCT06205602 | Phase 2 | Oct 15, 2024 | National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT06071767 | Phase 1/Phase 2 (Phase 2) | Jan 2, 2024 | Gilead Sciences, National Institute of Allergy and Infectious Diseases (NIAID), University of Oxford, University of Pittsburgh |
| NCT06031272 | Phase 1 | Dec 4, 2023 | AIDS Clinical Trials Group, National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT05729568 | Phase 2 | May 15, 2023 | Gilead Sciences |
| NCT05612178 | Phase 1 | Dec 29, 2022 | National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT05245292 | Phase 1 | Dec 15, 2022 | Cornell University, National Institute of Allergy and Infectious Diseases (NIAID), Rockefeller University, University of Pennsylvania |
| NCT05079451 | Phase 1 | Nov 1, 2021 | National Institute of Allergy and Infectious Diseases (NIAID), Rockefeller University, University of Pennsylvania |
| NCT04819347 | Phase 2 | May 1, 2021 | Frontier Biotechnologies Co., Ltd. |
| NCT04811040 | Phase 1 | Apr 8, 2021 | Gilead Sciences |
| NCT04720742 | Phase 2 | Feb 28, 2021 | Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milano, Hospital General Universitario Gregorio Marañon, IrsiCaixa, University of Granada, Utrecht University |
| NCT04560569 | Phase 2 | Dec 25, 2020 | Frontier Biotechnologies Co., Ltd. |
| NCT04250636 | Phase 1 | Feb 28, 2020 | Cornell University, National Institute of Allergy and Infectious Diseases (NIAID), Rockefeller University, University of Pennsylvania |
| NCT04173819 | Phase 1/Phase 2 (Phase 2) | Dec 1, 2019 | International AIDS Vaccine Initiative, Rockefeller University, University of Washington |
| NCT03837756 | Phase 2 | May 6, 2019 | Aalborg University, Aarhus University, The Peter Doherty Institute, University of Copenhagen, University of Southern Denmark, University of Utah |
| NCT03719664 | Phase 2 | Dec 17, 2018 | Frontier Biotechnologies Co., Ltd. |
| NCT03571204 | Phase 1 | Sep 10, 2018 | National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT03588715 | Phase 1 | Aug 1, 2018 | Merck, National Institute of Allergy and Infectious Diseases (NIAID), Philadelphia Fight, Rockefeller University, The Wistar Institute, University of Pennsylvania |
| NCT03554408 | Phase 1 | Jun 30, 2018 | Rockefeller University |
| NCT03526848 | Phase 1 | Jun 5, 2018 | National Institute of Allergy and Infectious Diseases (NIAID), Ragon Institute of MGH, MIT and Harvard, Rockefeller University, Yeshiva University |
Showing 20 of 30 trials
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Organizations
Research & Development (34)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Rockefeller University | Academic/Hospital | 15 | 11 | 2 | 2014 |
| National Institute of Allergy and Infectious Diseases (NIAID) | Government | 11 | 6 | 2 | 2015 |
| Cornell University | Academic/Hospital | 4 | 0 | 2 | 2014 |
| University of Cologne | Academic/Hospital | 4 | 0 | 2 | 2014 |
| University of Pennsylvania | Academic/Hospital | 4 | 0 | 1 | 2018 |
| Aarhus University | Academic/Hospital | 3 | 2 | 1 | 2016 |
| Frontier Biotechnologies Co., Ltd. | For profit | 3 | 3 | 1 | 2018 |
| Gilead Sciences | For profit | 3 | 2 | 2 | 2021 |
| Aalborg University | Academic/Hospital | 2 | 0 | 1 | 2017 |
| The Peter Doherty Institute | Academic/Hospital | 2 | 0 | 2 | 2017 |
| University of Copenhagen | Academic/Hospital | 2 | 0 | 1 | 2017 |
| University of Oxford | Academic/Hospital | 2 | 1 | 1 | 2024 |
| University of Southern Denmark | Academic/Hospital | 2 | 0 | 1 | 2017 |
| Yeshiva University | Academic/Hospital | 2 | 0 | 2 | 2015 |
| AIDS Clinical Trials Group | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Austin Health | Academic/Hospital | 1 | 0 | 1 | 2017 |
| Bill and Melinda Gates Foundation | Academic/Hospital | 1 | 0 | 1 | 2015 |
| Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milano | Academic/Hospital | 1 | 0 | 1 | 2021 |
| Harvard University | Academic/Hospital | 1 | 0 | 1 | 2014 |
| Herning Hospital | Academic/Hospital | 1 | 0 | 1 | 2017 |
34 organizations
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