CDEK by Data4ThePeople
Drugs
Search by NameFDA Approval TrendsAdvanced SearchFDA Approved Drugs
Organizations
Search by NameOrganization TrendsAdvanced Search
IndicationsMechanismsTrialsFDA Approvals
About
About CDEKGlossaryAdvanced Search GuideSearch by Name
Drugs
Search by NameFDA Approval TrendsAdvanced SearchFDA Approved Drugs
Organizations
Search by NameOrganization TrendsAdvanced Search
IndicationsMechanismsTrialsFDA Approvals
About
About CDEKGlossaryAdvanced Search GuideSearch by Name
← All indications

Pulmonary Alveolar Proteinosis

A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. This disease is often related to, congenital or acquired, impaired processing of PULMONARY SURFACTANTS by alveolar macrophages, a process dependent on GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR.

Drugs by status

Phase 3 trials (1)

  • sargramostim

Phase 2 trials (4)

  • vitamin c
  • rituximab
  • b multivitamins
  • methionine

Phase 1 trials (2)

  • Filgrastim
  • liberase

Organizations

Organization Involved with Phase 3 Indications (6)

  • Savara Inc.
  • University of London
  • University of Pavia
  • University of Cincinnati
  • Agenzia Italiana del Farmaco
  • Ruhrlandklinik University Hospital, Essen, Germany

Organization Involved with Phase 2 Indications (12)

  • Genentech
  • Genzyme
  • Huazhong University of Science and Technology
  • Nanjing University
  • Niigata University Medical & Dental Hospital
  • University of Rochester
  • Virginia Commonwealth University
  • East Carolina University
  • Peking University
  • Tsinghua University
  • Assistance Publique - Hôpitaux de Paris
  • APHP - Hôpital Necker

Organization Involved with Phase 1 Indications (5)

  • National Institutes of Health (NIH)
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • Celerion
  • National Center for Advancing Translational Science (NCATS)
  • Healeon Medical Inc

ICD-10 crosswalk

  • J84.01 — Alveolar proteinosis

CDEK

The Clinical Drug Experience Knowledgebase — tracking drugs, sponsoring organizations, and clinical trials from first-in-human testing through approval.

Browse

  • Drugs
  • Organizations
  • Trials

About

  • About CDEK
  • Glossary

Built and maintained by Data4ThePeople.

YOU AGREE THAT THE INFORMATION PROVIDED ON THIS WEBSITE IS PROVIDED "AS IS", WITHOUT ANY WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING WITHOUT LIMITATION WARRANTIES OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE, OR NON-INFRINGEMENT OF ANY THIRD-PARTY PATENT, COPYRIGHT, OR ANY OTHER THIRD-PARTY RIGHT. IN NO EVENT SHALL THE CREATORS OF THE WEBSITE OR WASHINGTON UNIVERSITY BE LIABLE FOR ANY DIRECT, INDIRECT, SPECIAL, OR CONSEQUENTIAL DAMAGES ARISING OUT OF OR IN ANY WAY CONNECTED WITH THE WEBSITE, THE USE OF THE WEBSITE, OR THIS AGREEMENT, WHETHER IN BREACH OF CONTRACT, TORT OR OTHERWISE, EVEN IF SUCH PARTY IS ADVISED OF THE POSSIBILITY OF SUCH DAMAGES.