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methionine

Small moleculeexperimental

Methionine is an essential amino acid in humans. Compared to other amino acids, methionine has particularly decisive biosynthetic roles. It is the precursor to the amino acid cysteine and the pervasive methylation agent rSAM. Methionine is required for protein synthesis, which is initiated by N-formylmethionine-sRNA. — Wikipedia

Clinical trial activity

10 trials · 20 clinical orgs · 0 marketing orgs

Phase 1
2
Phase 2
3
Phase 3
3
Phase 4
2

Earliest trial started Sep 1, 2007 (NCT00530738)

Timeline

2010s

  1. Jan 1, 2017

    Earliest Phase 3 Sponsor(trial)

  2. Jan 1, 2019

    Earliest Phase 1 Sponsor(trial)

2020s

  1. Jan 1, 2023

    Earliest Phase 2 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

  • methionineSupplementation

    methionine supplementation

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • lipoplus

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06183242Phase 2/Phase 3 (Phase 3)May 27, 2023Polysan, Ltd.
NCT05857215Phase 1Mar 5, 2021Galmed Pharmaceuticals Ltd, Quotient
NCT04701346N/AMar 1, 2021Charles University, Maastricht University, University of Oslo, University of Oxford
NCT04326322N/AMar 31, 2020University of British Columbia
NCT03887169Phase 1/Phase 2 (Phase 2)Apr 30, 2019APHP - Hôpital Necker, Assistance Publique - Hôpitaux de Paris
NCT03739333N/AFeb 26, 2019University of Lyon
NCT03418935Phase 3Apr 3, 2017BioEq, Irkutsk Regional Clinical Hospital, Leningrad Regional Clinical Hospital, Polysan, Ltd., State Budgetary Health Care Institution "City Hospital № 26", St. Petersburg Mechnikov State Medical Academy
NCT03416062Phase 3Apr 3, 2017Avicenna Medical Center, BioEq, Irkutsk Regional Clinical Hospital, Petrov Research Institute of Oncology, Polysan, Ltd., Regional Clinical oncologic center, Omsk region, State Budgetary Health Care Institution "City Hospital № 26", St. Petersburg Mechnikov State Medical Academy
NCT01814956Phase 4Mar 1, 2013B. Braun
NCT00530738Phase 4Sep 1, 2007B. Braun
Showing 10 of 10 trials
Page 1 / 1

Organizations

Research & Development (20)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Polysan, Ltd.For profit3312017
B. BraunFor profit2212007
BioEqFor profit2012017
Irkutsk Regional Clinical HospitalAcademic/Hospital2012017
State Budgetary Health Care Institution "City Hospital № 26"Academic/Hospital2012017
St. Petersburg Mechnikov State Medical AcademyAcademic/Hospital2012017
APHP - Hôpital NeckerAcademic/Hospital1012019
Assistance Publique - Hôpitaux de ParisAcademic/Hospital1112019
Avicenna Medical CenterAcademic/Hospital1012017
Charles UniversityAcademic/Hospital1012021
Galmed Pharmaceuticals LtdFor profit1112021
Leningrad Regional Clinical HospitalAcademic/Hospital1012017
Maastricht UniversityAcademic/Hospital1012021
Petrov Research Institute of OncologyAcademic/Hospital1012017
QuotientFor profit1012021
Regional Clinical oncologic center, Omsk regionAcademic/Hospital1012017
University of British ColumbiaAcademic/Hospital1112020
University of LyonAcademic/Hospital1112019
University of OsloAcademic/Hospital1112021
University of OxfordAcademic/Hospital1012021
20 organizations
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