red blood cells
Cell therapymarketed
Approved
Jun 1, 1818
Red blood cells (RBCs), referred to as erythrocytes in academia and medical publishing, also known as red cells, erythroid cells, and rarely haematids, are the most common type of blood cell and the vertebrate's principal means of delivering oxygen to the body tissues—via blood flow through the circulatory system. Erythrocytes take up oxygen in the lungs, or in fish the gills, and release it into tissues while squeezing through the body's capillaries. — Wikipedia
Clinical trial activity
92 trials · 145 clinical orgs · 0 marketing orgs
Phase 1
15
Phase 2
42
Phase 3
27
Phase 4
8
Earliest trial started Oct 1, 2001 (NCT00577096)
Timeline
Indications
Approved for
Studied for
- Acute Coronary Syndrome · Phase 1/Phase 2
- Anemia · Phase 4
- Anemia, Sickle Cell · Phase 3
- Angina, Unstable · Phase 3
- Aortic Aneurysm, Abdominal · Phase 2
- Arterial Occlusive Diseases · Phase 2
- Atherosclerosis · Phase 2
- beta-Thalassemia · Phase 3
- Bleeding Time · Phase 3
- Blood Transfusion · Phase 3
- Breast Neoplasms · Phase 3
- Cardiovascular Diseases · Phase 4
- Coronary Artery Disease · Phase 3
- Coronary Vasospasm · Phase 1/Phase 2
- Critical Illness · Phase 3
- Delivery, Obstetric · Phase 1
- Drugs, Investigational · Phase 2
- Endothelium · Phase 2
- Erythrocyte Transfusion · Phase 4
- Extracorporeal Membrane Oxygenation · Phase 3
- General Surgery · Phase 3
- Glucose Transporter Type 1 · Early Phase 1
- Health Services · Phase 4
- Healthy Volunteers · Phase 4
- Heart Arrest · Phase 1
- Heart Diseases · Phase 3
- Hematologic Diseases · Phase 3
- Hematologic Neoplasms · Phase 3
- Hematology · Phase 4
- Hemochromatosis · Phase 3
- Hemorrhage · Phase 3
- Hip Fractures · Phase 4
- Hypertension, Pulmonary · Phase 2
- Infant, Premature, Diseases · Phase 4
- Intensive Care Units · Phase 4
- Leukemia, Lymphocytic, Chronic, B-Cell · Phase 1
- Leukemia, Myeloid, Acute · Phase 1
- Multiple Sclerosis · Phase 1/Phase 2
- Multiple Trauma · Phase 1/Phase 2
- Myelodysplastic Syndromes · Phase 3
- Myocardial Infarction · Phase 3
- Neoplasm Metastasis · Phase 3
- Neoplasms · Phase 3
- Nitric Oxide · Phase 2
- Oxidative Stress · Early Phase 1
- Pancreatic Neoplasms · Early Phase 1
- Pneumonia · Phase 3
- Postpartum Hemorrhage · Phase 3
- Precursor Cell Lymphoblastic Leukemia-Lymphoma · Phase 1
- Respiratory Distress Syndrome · Phase 3
- Retinopathy of Prematurity · Phase 2
- Sepsis · Phase 3
- Sex Characteristics · Phase 4
- Shock, Cardiogenic · Phase 1
- Shock, Hemorrhagic · Phase 3
- Shock, Septic · Phase 3
- Stroke · Phase 3
- Subarachnoid Hemorrhage · Phase 3
- Thoracic Surgery · Phase 3
- Thromboembolism · Phase 3
- Transfusion Reaction · Phase 1
- Traumatology · Phase 3
- Wounds and Injuries · Phase 3
Mechanism of action
- ErythrocyteSupplementation
Erythrocyte supplementation
Approval history
- approvedJun 1, 1818
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaRed blood cell ↗
- NCATS2K524Y8G0J ↗
Also known as
- rbc
- rbc
- red blood cell
- red blood cells
- red cells
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06526533 | Phase 3 | Sep 30, 2025 | Berry Consultants, Monash University |
| NCT07015437 | Phase 2 | Sep 19, 2025 | Cerus Corporation |
| NCT06840756 | Phase 4 | Aug 1, 2025 | Canadian Institutes of Health Research (CIHR), McMaster University |
| NCT06462027 | Phase 1 | Nov 15, 2024 | New York University |
| NCT06560164 | N/A | Oct 1, 2024 | University of Amsterdam, ZonMw: The Netherlands Organisation for Health Research and Development |
| NCT06495294 | N/A | Aug 31, 2024 | Canadian Blood Services, Hamilton Health Sciences Corporation, Health Sciences North Research Institute, Kingston Health Sciences Centre, Queen's University, Belfast, Unity Health Toronto, University of Toronto, University of Western Ontario |
| NCT06430671 | Phase 1/Phase 2 (Phase 2) | Jun 18, 2024 | Cellerys AG, Novartis, SCOPE International AG, Tetec AG |
| NCT05841706 | Early Phase 1 (Phase 1) | Dec 30, 2023 | University of California, Los Angeles |
| NCT05835882 | N/A | Jun 1, 2023 | Universita' Cattolica del Sacro Cuore |
| NCT05814094 | N/A | May 31, 2023 | Monash University, University of New South Wales, University of Sydney |
| NCT05669872 | N/A | Feb 28, 2023 | University of Ulsan |
| NCT05699005 | Phase 1 | Feb 28, 2023 | Centre Hospitalier de Lens, Rouen Normandy University, University of Burgundy, University of Caen-Normandie, University of Lille, University of Picardie Jules Verne |
| NCT05612919 | N/A | Jan 31, 2023 | Banc de Sang i Teixits, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona |
| NCT05405426 | N/A | Jan 31, 2023 | Harvard University |
| NCT05100212 | Phase 2 | Nov 30, 2021 | Fresenius, Universita' Cattolica del Sacro Cuore |
| NCT04814264 | Early Phase 1 (Phase 1) | Nov 30, 2021 | Canadian Institutes of Health Research (CIHR), McMaster University |
| NCT04920045 | N/A | Nov 30, 2021 | University of Chicago |
| NCT04431999 | Phase 3 | Sep 30, 2020 | Direction Centrale du Service de Santé des Armées, Ecoles militaires de santé de Lyon-Bron, Floralis, TIMC-IMAG |
| NCT04591574 | N/A | Sep 23, 2020 | University of Edinburgh, University of Oxford |
| NCT03981484 | Phase 2 | Jan 31, 2020 | University of Arizona |
Showing 20 of 92 trials
Page 1 / 5
Organizations
Research & Development (145)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Heart, Lung, and Blood Institute (NHLBI) | Government | 10 | 0 | 3 | 2003 |
| Canadian Institutes of Health Research (CIHR) | Academic/Hospital | 6 | 0 | 3 | 2011 |
| Harvard University | Academic/Hospital | 6 | 4 | 3 | 2009 |
| Canadian Blood Services | Academic/Hospital | 4 | 0 | 3 | 2006 |
| Cerus Corporation | For profit | 4 | 4 | 2 | 2012 |
| Columbia University | Academic/Hospital | 4 | 2 | 3 | 2010 |
| Duke University | Academic/Hospital | 4 | 1 | 3 | 2005 |
| Rutgers University | Academic/Hospital | 4 | 3 | 1 | 2003 |
| University of Pittsburgh | Academic/Hospital | 4 | 1 | 1 | 2009 |
| Emory University | Academic/Hospital | 3 | 2 | 3 | 2009 |
| Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta | Academic/Hospital | 3 | 2 | 2 | 2018 |
| Johns Hopkins University | Academic/Hospital | 3 | 1 | 3 | 2010 |
| Mayo Clinic | Academic/Hospital | 3 | 2 | 3 | 2008 |
| University of Copenhagen | Academic/Hospital | 3 | 2 | 3 | 2004 |
| University of Ottawa | Academic/Hospital | 3 | 3 | 2 | 2011 |
| Banc de Sang i Teixits | Academic/Hospital | 2 | 1 | 2 | 2018 |
| Baylor University | Academic/Hospital | 2 | 0 | 1 | 2006 |
| Blood Center of Wisconsin | Academic/Hospital | 2 | 1 | 1 | 2012 |
| Case Western Reserve University | Academic/Hospital | 2 | 2 | 2 | 2013 |
| Cornell University | Academic/Hospital | 2 | 0 | 2 | 2010 |
145 organizations
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