pelubiprofen
Small moleculeexperimental
Clinical trial activity
15 trials · 3 clinical orgs · 0 marketing orgs
Phase 1
8
Phase 2
6
Phase 3
5
Phase 4
1
Earliest trial started Oct 1, 2010 (NCT01781702)
Timeline
Indications
Approved for
Studied for
- Acute Pain · Phase 2
- Arthritis, Rheumatoid · Phase 3
- Back Pain · Phase 3
- Celecoxib · Phase 3
- Drugs, Investigational · Phase 3
- Dysmenorrhea · Phase 3
- Fever · Phase 3
- Healthy Volunteers · Phase 1
- Osteoarthritis · Phase 1
- Osteoarthritis, Knee · Phase 4
- Pharmacokinetics · Phase 1
- Respiratory Tract Infections · Phase 3
- Traumatology · Phase 3
Mechanism of action
- Cyclooxygenase-2INHIBITOR
PTGS2 inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
CC(C(=O)O)c1ccc(/C=C2\CCCCC2=O)cc1- Mol. weight
- 258.32 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL69308 ↗
Also known as
- 2-(4-((2-oxocyclohexylidene)methyl)phenyl)propionic acid
- 2-ocmpp
- cs 670
- cs-670
- dw330sr
- dw340
- pelubiprofen
- pelubiprofen
- pelubiprofen
- pelubiprofen
- pelubiprofen
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07032558 | Phase 1 | Sep 20, 2025 | Big Leap Research, Daewon Pharmaceutical Co., Ltd., Hai Phong Medical University |
| NCT07060209 | Phase 1 | Sep 20, 2025 | Big Leap Research, Daewon Pharmaceutical Co., Ltd., Hai Phong Medical University |
| NCT04541134 | Phase 3 | Sep 30, 2020 | Daewon Pharmaceutical Co., Ltd. |
| NCT05214677 | Phase 1 | Aug 15, 2020 | Daewon Pharmaceutical Co., Ltd. |
| NCT05214690 | Phase 1 | Aug 13, 2020 | Daewon Pharmaceutical Co., Ltd. |
| NCT03874247 | Phase 3 | Feb 25, 2019 | Daewon Pharmaceutical Co., Ltd. |
| NCT03424707 | Phase 2 | Mar 4, 2016 | Daewon Pharmaceutical Co., Ltd. |
| NCT02380976 | Phase 1 | Oct 1, 2015 | Daewon Pharmaceutical Co., Ltd. |
| NCT02682524 | Phase 4 | Aug 1, 2015 | Daewon Pharmaceutical Co., Ltd. |
| NCT02375633 | Phase 3 | Apr 1, 2014 | Daewon Pharmaceutical Co., Ltd. |
| NCT02071381 | Phase 1 | Apr 1, 2014 | Daewon Pharmaceutical Co., Ltd. |
| NCT01870102 | Phase 1 | Jun 3, 2013 | Daewon Pharmaceutical Co., Ltd. |
| NCT01779271 | Phase 3 | Jan 1, 2013 | Daewon Pharmaceutical Co., Ltd. |
| NCT01776697 | Phase 1 | Mar 1, 2012 | Daewon Pharmaceutical Co., Ltd. |
| NCT01781702 | Phase 3 | Oct 1, 2010 | Daewon Pharmaceutical Co., Ltd. |
Showing 15 of 15 trials
Page 1 / 1
Organizations
Research & Development (3)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Daewon Pharmaceutical Co., Ltd. | For profit | 15 | 13 | 4 | 2010 |
| Big Leap Research | For profit | 2 | 0 | 1 | 2025 |
| Hai Phong Medical University | Academic/Hospital | 2 | 2 | 1 | 2025 |
3 organizations
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