CDEK
← Mechanisms of action

KRAS

SINGLE PROTEINHomo sapiens
Preferred name: GTPase KRas ChEMBL ↗

Linked proteins

Drugs acting on this target (105)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
adagrasib (Krazati)AntagonistapprovedSmall moleculeKRAS antagonist
d3s-001AntagonistexperimentalSmall moleculeKRAS
hbi-2438AntagonistexperimentalSmall moleculeKras
hrs-4642AntagonistexperimentalSmall moleculeKras
hs-10370AntagonistexperimentalSmall moleculeKRAS
sotorasib (LUMAKRAS)AntagonistapprovedSmall moleculeKRAS antagonist
azd4785Antisense inhibitorexperimentalNucleic acidKRAS antisense inhibitor
mesenchymal stromal cells-derived exosomes with kras g12d sirnaAntisense inhibitorexperimentalBiologicalKRAS antisense inhibitor
sig12d loderAntisense inhibitorexperimentalNucleic acidKRAS antisense inhibitor
arv-806DegraderexperimentalSmall moleculeKRAS degrader
asp5834DegraderexperimentalSmall moleculeKRAS degrader
abo2102Immunity, activeexperimentalVaccineKRAS immunity, active
edc-kras vaccineImmunity, activeexperimentalVaccineKRAS immunity, active
kras peptide vaccineImmunity, activeexperimentalVaccineKRAS immunity, active
kras-mutated mrna vaccineImmunity, activeexperimentalVaccineKRAS immunity, active
mdc3/8 vaccineImmunity, activeexperimentalVaccineKRAS immunity, active
mdc3/8-kras vaccineImmunity, activeexperimentalVaccineKRAS immunity, active
mkrasvaxImmunity, activeexperimentalVaccineKRAS immunity, active
re001 t cellImmunity, activeexperimentalCell therapyKRAS immunity, active
anoc-001Immunity, passiveexperimentalCell therapyKRAS immunity, passive
anti-kras g12v mtcrImmunity, passiveexperimentalCell therapyKRAS immunity, passive
ix001Immunity, passiveexperimentalCell therapyKRAS immunity, passive
kras tcr-transduced pblImmunity, passiveexperimentalCell therapyKRAS immunity, passive
kras-epha-2-car-dcImmunity, passiveexperimentalCell therapyKRAS immunity, passive
kras-specific autologous tcr-t cell injectionImmunity, passiveexperimentalCell therapyKRAS immunity, passive
nt-112Immunity, passiveexperimentalCell therapyKRAS immunity, passive
tcr1020-cd8 t cellsImmunity, passiveexperimentalCell therapyKRAS immunity, passive
yk0901Immunity, passiveexperimentalCell therapyKRAS immunity, passive
absk141InhibitorexperimentalSmall moleculeKRAS inhibitor
adagrasib (Krazati)InhibitorapprovedSmall moleculeGTPase KRas inhibitor
alta3263InhibitorexperimentalSmall moleculeKRAS inhibitor
amg 410InhibitorexperimentalSmall moleculeKRAS inhibitor
an9025InhibitorexperimentalSmall moleculeKRAS inhibitor
anx-510InhibitorexperimentalSmall moleculeKRAS inhibitor
asp4396InhibitorexperimentalSmall moleculeKRAS inhibitor
azd0022InhibitorexperimentalSmall moleculeKRAS inhibitor
b013InhibitorexperimentalRecombinant proteinKRAS inhibitor
bbo-10203InhibitorexperimentalSmall moleculeKRAS inhibitor
bbo-11818InhibitorexperimentalSmall moleculeKRAS inhibitor
bbo-8520InhibitorexperimentalSmall moleculeKRAS inhibitor
bebt-607InhibitorexperimentalSmall moleculeKRAS inhibitor
bgb-53038InhibitorexperimentalSmall moleculeKRAS inhibitor
bi 1701963InhibitorexperimentalSmall moleculeKRAS inhibitor
bi 1823911InhibitorexperimentalSmall moleculeKRAS inhibitor
bi 3706674InhibitorexperimentalSmall moleculeKRAS inhibitor
bpi-572270InhibitorexperimentalSmall moleculeKRAS inhibitor
d-1553InhibitorexperimentalSmall moleculeKRAS inhibitor
d3s-003InhibitorexperimentalSmall moleculeKRAS inhibitor
dcc-3116InhibitorexperimentalSmall moleculeKRAS inhibitor
eras-0015InhibitorexperimentalSmall moleculeKRAS inhibitor
eras-4001InhibitorexperimentalmAbKRAS inhibitor
fmc-376InhibitorexperimentalSmall moleculeKRAS inhibitor
g12dInhibitorexperimentalSmall moleculeKRAS inhibitor
gdc-6036InhibitorexperimentalSmall moleculeKRAS inhibitor
gec255InhibitorexperimentalSmall moleculeKRAS inhibitor
gfh276InhibitorexperimentalSmall moleculeKRAS inhibitor
gfh375InhibitorexperimentalSmall moleculeKRAS inhibitor
gfh925InhibitorexperimentalSmall moleculeKRAS inhibitor
gh35InhibitorexperimentalSmall moleculeKRAS inhibitor
glumetinibInhibitorexperimentalSmall moleculeKRAS inhibitor
hrs-2329InhibitorexperimentalSmall moleculeKRAS inhibitor
hrs-7058InhibitorexperimentalSmall moleculeKRAS inhibitor
hs-10529InhibitorexperimentalSmall moleculeKRAS inhibitor
hyp-2090ptsaInhibitorexperimentalSmall moleculeKRAS inhibitor
incb161734InhibitorexperimentalSmall moleculeKRAS inhibitor
incb186748InhibitorexperimentalSmall moleculeKRAS inhibitor
jab-21822InhibitorexperimentalSmall moleculeKRAS inhibitor
jab-23e73InhibitorexperimentalSmall moleculeKRAS inhibitor
jdq443InhibitorexperimentalSmall moleculeKRAS inhibitor
jnj-74699157InhibitorexperimentalSmall moleculeKRAS inhibitor
jyp0015InhibitorexperimentalSmall moleculeKRAS inhibitor
jyp0015InhibitorexperimentalSmall moleculeKRAS inhibitor
kqb365InhibitorexperimentalSmall moleculeKRAS inhibitor
kqb548InhibitorexperimentalSmall moleculeKRAS inhibitor
luna18InhibitorexperimentalSmall moleculeKRAS inhibitor
ly3499446InhibitorexperimentalSmall moleculeKRAS inhibitor
ly3537982InhibitorexperimentalSmall moleculeKRAS inhibitor
ly3962673InhibitorexperimentalSmall moleculeKRAS inhibitor
ly4066434InhibitorexperimentalSmall moleculeKRAS inhibitor
mk-4318InhibitorexperimentalSmall moleculeKRAS inhibitor
mrtx1133InhibitorexperimentalSmall moleculeKRAS inhibitor
pf-07934040InhibitorexperimentalSmall moleculeKRAS inhibitor
pt0253InhibitorexperimentalSmall moleculeKRAS inhibitor
qcz484InhibitorexperimentalSmall moleculeKRAS inhibitor
qlc1101InhibitorexperimentalSmall moleculeKRAS inhibitor
qtx3034InhibitorexperimentalSmall moleculeKRAS inhibitor
qtx3046InhibitorexperimentalSmall moleculeKRAS inhibitor
qtx3544InhibitorexperimentalSmall moleculeKRAS inhibitor
rmc-4630InhibitorexperimentalSmall moleculeKRAS inhibitor
rmc-9805InhibitorexperimentalSmall moleculeKRAS inhibitor
rnk08954InhibitorexperimentalSmall moleculeKRAS inhibitor
rnk08954-01InhibitorexperimentalSmall moleculeKRAS inhibitor
rx001InhibitorexperimentalSmall moleculeKRAS inhibitor
shr-4642InhibitorexperimentalSmall moleculeKRAS inhibitor
sotorasib (LUMAKRAS)InhibitorapprovedSmall moleculeGTPase KRas inhibitor
sy-5933InhibitorexperimentalSmall moleculeKRAS inhibitor
tln-372InhibitorexperimentalSmall moleculeKRAS inhibitor
tno155InhibitorexperimentalSmall moleculeKRAS inhibitor
tsn1611InhibitorexperimentalSmall moleculeKRAS inhibitor
v941InhibitorexperimentalSmall moleculeKRAS inhibitor
vs-7375InhibitorexperimentalSmall moleculeKRAS inhibitor
wef-001InhibitorexperimentalSmall moleculeKRAS inhibitor
zg19018InhibitorexperimentalSmall moleculeKRAS inhibitor
zg2001InhibitorexperimentalSmall moleculeKRAS inhibitor
yl-15293Ultraviolet filterexperimentalSmall moleculeKRAS ultraviolet filter