magnesium citrate
Small moleculeexperimental
Magnesium citrate (3:2), also called trimagnesium dicitrate, trimagnesium citrate, or the ambiguous name magnesium citrate. The substance may come as anhydrous or hydrated salt with varying properties. — Wikipedia
Clinical trial activity
51 trials · 52 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
21
Phase 3
12
Phase 4
16
Earliest trial started Jul 1, 2005 (NCT00312481)
Timeline
Indications
Approved for
Studied for
- Anemia, Refractory · Phase 3
- Calciphylaxis · Phase 3
- Chronic Kidney Disease-Mineral and Bone Disorder · Phase 2/Phase 3
- Colitis, Ulcerative · Phase 4
- Colon · Phase 4
- Colonic Diseases · Phase 4
- Colonic Polyps · Phase 3
- Colonoscopy · Phase 4
- Colorectal Neoplasms · Phase 3
- Constipation · Phase 4
- COVID-19 · Phase 1/Phase 2
- Diabetic Nephropathies · Phase 2
- Gastrointestinal Hemorrhage · Phase 3
- Glycemic Control · Phase 2
- Glycocalyx · Phase 3
- Healthy Volunteers · Phase 4
- Hemodynamics · Phase 4
- Hypertension · Phase 4
- Hyponatremia · Phase 4
- Intellectual Disability · Phase 2
- Intestinal Diseases · Phase 3
- Intestine, Large · Phase 4
- Kidney Calculi · Phase 4
- Magnesium Deficiency · Phase 4
- Magnesium Sulfate · Phase 2
- Neurodevelopmental Disorders · Phase 3
- Osteoporosis · Phase 3
- Prehypertension · Phase 1/Phase 2
- Premature Birth · Phase 3
- Urolithiasis · Phase 3
Mechanism of action
- Unspecified targetOTHER
Supplement
- Unspecified targetOTHER
Osmotic laxative
Chemistry & pharmacology
Loading structure…
SMILES
O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Mg+2].[Mg+2].[Mg+2]- Mol. weight
- 451.11 g/mol
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3989480 ↗
- WikipediaMagnesium citrate (3:2) ↗
- ChEMBLCHEMBL2105061 ↗
- WikipediaMagnesium citrate ↗
Also known as
- citramag
- citramag
- citric acid magnesium salt
- magcit
- mag cit
- mag diasporal 300
- magnesium citrate
- magnesium citrate
- magnesium citrate
- magnesium citrate
- magnesium citrate
- magnesium citrate
- magnesium citrate
- mg citrate
- potassium magnesium citrate
- potassium magnesium citrate
- potassium-magnsium citrate
- trimagnesium dicitrate
- trimagnesium dicitrate
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07309640 | N/A | Jan 1, 2026 | Univerisiti Sains Malaysia |
| NCT06321796 | Phase 2 | Feb 27, 2024 | Gut-Brain-Axis Therapeutics Inc., Pitt Hopkins Research Foundation |
| NCT05998863 | Phase 3 | Jan 1, 2024 | The University of Texas, Dallas |
| NCT05597150 | Phase 2 | Jan 31, 2023 | Southern Medical University |
| NCT05145309 | Phase 2 | Jan 1, 2022 | The University of Texas, Dallas |
| NCT04651088 | Early Phase 1 (Phase 1) | Dec 1, 2021 | The University of Texas, Dallas |
| NCT05018221 | Phase 3 | Aug 26, 2021 | Australasian Kidney Trials Network, Salford Royal Foundation NHS Trust, University of Sydney, Waitemata District Health Board |
| NCT04941703 | Phase 1/Phase 2 (Phase 2) | Jun 25, 2021 | Vanderbilt University |
| NCT04598880 | Phase 4 | Nov 6, 2020 | Clinica Universidad de Navarra, Hospital del Mar (Barcelona, Spain), Institut Hospital del Mar d'Investigacions Mèdiques |
| NCT04613154 | N/A | Sep 24, 2020 | Orebro University |
| NCT04462796 | N/A | Jul 10, 2020 | OSF HealthCare |
| NCT04132427 | Phase 2 | Sep 30, 2019 | Arizona State University, Pitt Hopkins Research Foundation |
| NCT04095975 | Phase 4 | Aug 28, 2019 | University of Wisconsin |
| NCT04021381 | Phase 3 | Jul 31, 2019 | Assistance Publique - Hôpitaux de Paris |
| NCT03824379 | Phase 2 | Jun 1, 2019 | Ain Shams University |
| NCT03812380 | Phase 3 | Jan 1, 2019 | The University of Texas, Dallas |
| NCT03698474 | Phase 4 | Oct 25, 2018 | Teaching Hospital Královské Vinohrady (FNKV), Tomas Bata Hospital Zlin |
| NCT03716609 | N/A | Oct 23, 2018 | Academia Sinica, Taiwan, Government of Taiwan, Institute of Biomedical Sciences, Academia Sinica, Taipei Veteran General hospital |
| NCT03632590 | N/A | Mar 27, 2018 | Nedmag, University of Groningen |
| NCT03581149 | Phase 4 | Mar 26, 2018 | American University of Beirut |
Showing 20 of 51 trials
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Organizations
Research & Development (52)
52 organizations
Page 1 / 3