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← All drugs Report issue

etoricoxib

Trade name: Gencox

Small moleculeexperimental

Etoricoxib, sold under brand names including Arcoxia, Exinef and Nucoxia is a selective COX-2 inhibitor developed and commercialized by Merck. It is approved in 63 countries worldwide as of 2007, except the United States where the Food and Drug Administration sent a Non Approvable Letter to Merck and required them to provide additional data. — Wikipedia

Clinical trial activity

109 trials · 98 clinical orgs · 0 marketing orgs

Phase 1
11
Phase 2
51
Phase 3
36
Phase 4
36

Earliest trial started Jun 1, 1998 (NCT00242489)

Timeline

1990s

  1. Jan 1, 1998

    Earliest Phase 2 Sponsor(trial)

2000s

  1. Jan 1, 2000

    Earliest Phase 3 Sponsor(trial)

  2. Jan 1, 2002

    Earliest Phase 1 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

Cc1ccc(-c2ncc(Cl)cc2-c2ccc(S(C)(=O)=O)cc2)cn1
Mol. weight
358.85 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No
Delivery
Oral

Oral

Yes

Parenteral

No

Topical

No

Sources

Also known as

  • 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine
  • 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine
  • 5-chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl
  • 5-chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl
  • 5-chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridine
  • 5-chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridine
  • arcoxia
  • arcoxia
  • arcoxia
  • arcoxia
  • arcoxia
  • etobrix
  • etocox
  • etoricoxib
  • etoricoxib
  • etoricoxib
  • etoricoxib
  • etoricoxib
  • etoricoxib
  • etoricoxib
  • etoricoxib
  • etoricoxibum
  • etoricoxibum
  • etoxib
  • etropain
  • l791456
  • l791456
  • l-791456
  • mk0663
  • mk0663
  • mk 0663
  • mk-0663
  • mk-0663
  • mk-0663
  • mk-0663
  • mk-0663
  • nucoxia
  • torcoxia

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07143318Phase 1Jun 5, 2025Sichuan Kelun Pharmaceutical Research Institute Co., Ltd.
NCT06863701Phase 3Jan 27, 2025Consultorio Médico "Dr. Rodrigo Suárez Otero", Laboratorios Silanes S.A. de C.V.
NCT06863662Phase 3Sep 18, 2024Laboratorios Silanes S.A. de C.V., OAXACA SITE MANAGEMENT ORGANIZATION, SC
NCT06791434Phase 4Aug 30, 2024MIT World Peace University
NCT05683574Phase 3Jun 30, 2024Eurofarma Laboratorios S.A.
NCT06517823Phase 3Apr 26, 2024Clinical Research Institute S.C., Laboratorios Silanes S.A. de C.V.
NCT06001112N/ASep 1, 2023Guangdong Provincial Hospital of Traditional Chinese Medicine
NCT05936281Phase 2Jun 30, 2023Fudan University, GeneScience Pharmaceuticals Co., Ltd.
NCT05536856Phase 4Oct 15, 2022Al Azhar University
NCT05142098Early Phase 1 (Phase 1)Jan 1, 2022Dow University of Health Sciences, Duke University
NCT05256342N/ADec 30, 2021Technion University
NCT04968158Phase 3Nov 29, 2021Clinical Research Institute S.C., Icaro Investigación en Medicina S.A. de C.V., Laboratorios Silanes S.A. de C.V., Mediadvance Clinical S.A.P.I. de C.V.
NCT05791721Phase 4Oct 11, 2021University of Belgrade
NCT05995912Phase 2Sep 29, 2021Laboratorios Liomont, OAXACA SITE MANAGEMENT ORGANIZATION, SC
NCT04830579Phase 1Apr 10, 2021CRO ClinPharmInvest, Pharmtechnology LLC
NCT05014490Phase 1Feb 24, 2021Darnitsa Pharmaceutical Company, SFBC Anapharm
NCT05532280Phase 1Dec 28, 2020Future University in Egypt
NCT05533073Phase 1Aug 3, 2020Laboratorios Silanes S.A. de C.V., Universidad Autonoma de Nuevo Leon
NCT04462666Phase 2Jul 1, 2020Shanghai University of Traditional Chinese Medicine
NCT04883034N/AJun 1, 2020Gadjah Mada University
Showing 20 of 109 trials
Page 1 / 6

Organizations

Research & Development (98)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
MerckFor profit473141998
Laboratorios Silanes S.A. de C.V.For profit5522020
University of OsloAcademic/Hospital4442004
Karolinska InstituteAcademic/Hospital3322008
Osaka UniversityAcademic/Hospital3132010
Tel Aviv UniversityAcademic/Hospital3322006
Chung Shan Medical UniversityAcademic/Hospital2222007
Clinical Research Institute S.C.For profit2012021
Foisor Orthopedics Clinical HospitalAcademic/Hospital2222014
Hebrew UniversityAcademic/Hospital2112008
OAXACA SITE MANAGEMENT ORGANIZATION, SCFor profit2022021
Technion UniversityAcademic/Hospital2122010
University of RegensburgAcademic/Hospital2212008
Al Azhar UniversityAcademic/Hospital1112022
Analgesic SolutionsFor profit1112011
Argentine Tennis AssociationAcademic/Hospital1112009
Autonomous University of MadridAcademic/Hospital1012010
Azienda Sanitaria Locale 4, TeramoGovernment1112011
Baerum HospitalAcademic/Hospital1012004
Bangladesh Medical UniversityAcademic/Hospital1112016
98 organizations
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