← Mechanisms of action
CALCA
SINGLE PROTEINHomo sapiens
Preferred name: Calcitonin gene-related peptide 1 ChEMBL ↗
Linked proteins
Drugs acting on this target (11)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| IL-23/CGRP bispecific antibody | Antagonist | experimental | mAb | CALCA antagonist |
| js010 | Antagonist | experimental | Small molecule | CALCA antagonist |
| zavegepant (zavzpret) | Antagonist | approved | Small molecule | CALCA antagonist |
| amg 223 | Inhibitor | experimental | Small molecule | CALCA inhibitor |
| bi 44370 | Inhibitor | experimental | Small molecule | CALCA inhibitor |
| eptinezumab (Vyepti) | Inhibitor | approved | mAb | CALCA |
| galcanezumab-gnlm (emgality) | Inhibitor | approved | mAb | CALCA inhibitor |
| htl0022562 | Inhibitor | experimental | Small molecule | CALCA inhibitor |
| telcagepant potassium | Inhibitor | experimental | Small molecule | CALCA inhibitor |
| ub-313 | Inhibitor | experimental | Vaccine | CALCA inhibitor |
| Vazegepant | Inhibitor | experimental | Small molecule | CALCA inhibitor |