CDEK
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unfractionated heparin

Small moleculeexperimental

Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. Heparin is a blood anticoagulant that increases the activity of antithrombin. It is used in the treatment of heart attacks and unstable angina. It can be given intravenously or by injection under the skin. Its anticoagulant properties make it useful to prevent blood clotting in blood specimen test tubes and kidney dialysis machines. — Wikipedia

Clinical trial activity

48 trials · 72 clinical orgs · 0 marketing orgs

Phase 1
2
Phase 2
14
Phase 3
13
Phase 4
15

Earliest trial started Jan 1, 2013 (NCT01823393)

Timeline

2010s

  1. Jan 1, 2016

    Earliest Phase 3 Sponsor(trial)

  2. Jan 1, 2018

    Earliest Phase 2 Sponsor(trial)

2020s

  1. Jan 1, 2020

    Earliest Phase 1 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

Chemistry & pharmacology

Chirality
Single Stereoisomer
Inorganic
No
Polymer
No
Delivery
Parenteral
Availability
Discontinued

Oral

No

Parenteral

Yes

Topical

No

Sources

Also known as

  • ca heparin
  • calciparin
  • calciparine
  • calciparine
  • calciparine
  • calcium heparin
  • calcium heparinate
  • heparin
  • heparin
  • heparinate
  • heparinate
  • heparin-calcium
  • heparinic acid
  • heparinic acid
  • liquaemin
  • liquaemin
  • panheprin
  • unfractionated heparin
  • unfractionated heparin

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06861374N/AMay 31, 2025Jiao Tong University
NCT06517563Phase 1Aug 14, 2024VarmX B.V.
NCT06275555N/AAug 1, 2024Capital Medical University
NCT06442267Phase 4Jul 30, 2024Medical University of Vienna
NCT06375616Phase 4Apr 30, 2024Fudan University
NCT06276010N/AMar 1, 2024Capital Medical University
NCT05959252Phase 2Jan 1, 2024Sydney Local Health District
NCT06174961Phase 4Sep 22, 2023University of Copenhagen
NCT05204550Phase 2/Phase 3 (Phase 3)Jan 1, 2023Monash University, Murdoch University, The Peter Doherty Institute, University of Melbourne, University of New South Wales
NCT05184101Phase 2/Phase 3 (Phase 3)Oct 30, 2022Australian National University, Rush University, University of New South Wales, University of Sydney
NCT05555641Phase 2Oct 1, 2022Huazhong University of Science and Technology
NCT05255848Phase 2/Phase 3 (Phase 3)Jun 20, 2022Lady Reading Hospital, Pakistan
NCT05247424Phase 4Feb 15, 2022University of Ljubljana
NCT05191290Phase 4Jan 21, 2022University of Ljubljana
NCT05226442Phase 2/Phase 3 (Phase 3)Dec 1, 2021Medical University of Vienna
NCT05148026N/ANov 14, 2021University of Milano Bicocca
NCT04925167N/AJul 6, 2021Capital Medical University
NCT04725201Phase 4May 24, 2021University of Montreal
NCT04861922Phase 3Apr 20, 2021Central South University
NCT04635839N/ANov 15, 2020University of California, Los Angeles
Showing 20 of 48 trials
Page 1 / 3

Organizations

Research & Development (72)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Capital Medical UniversityAcademic/Hospital4422018
Australian National UniversityAcademic/Hospital3312020
University of LjubljanaAcademic/Hospital3322019
University of Sao PauloAcademic/Hospital3322020
University of TorontoAcademic/Hospital3222019
Huazhong University of Science and TechnologyAcademic/Hospital2222018
Medical University of ViennaAcademic/Hospital2222021
University of New South WalesAcademic/Hospital2012022
University of VermontAcademic/Hospital2012020
Aarhus UniversityAcademic/Hospital1112019
Albert Einstein Israelite HospitalAcademic/Hospital1012020
Assistance Publique - Hôpitaux de ParisAcademic/Hospital1112020
Beneficência Portuguesa de Sao PauloAcademic/Hospital1012020
Beni Suef UniversityAcademic/Hospital1112016
Brazilian Clinical Research InstituteAcademic/Hospital1112020
Brazilian Research In Intensive Care NetworkAcademic/Hospital1012020
Bristol-Myers SquibbFor profit1012019
Canadian Institutes of Health Research (CIHR)Academic/Hospital1012018
CancerCare ManitobaAcademic/Hospital1012018
Cedars-Sinai Medical CenterAcademic/Hospital1112019
72 organizations
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