diethylstilbestrol diphosphate
Trade name: stilphostrol
Small moleculewithdrawn
Approved
Jun 1, 1940
Fosfestrol, sold under the brand name Honvan and also known as diethylstilbestrol diphosphate (DESDP), is an estrogen medication which is used in the treatment of prostate cancer in men. It is given by slow intravenous infusion once per day to once per week or by mouth once per day. — Wikipedia
Clinical trial activity
0 trials · 0 clinical orgs · 2 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Timeline
Indications
Approved for
Mechanism of action
- Estrogen receptorAGONIST
Estrogen receptor agonist
Approval history
- withdrawnJun 1, 1940
Chemistry & pharmacology
Loading structure…
SMILES
CC/C(=C(/CC)c1ccc(OP(=O)(O)O)cc1)c1ccc(OP(=O)(O)O)cc1- Mol. weight
- 428.31 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
- Delivery
- Oral, Parenteral
- Availability
- Discontinued
Oral
Yes
Parenteral
Yes
Topical
No
Prodrug
Sources
- WikipediaFosfestrol ↗
- ChEMBLCHEMBL1200598 ↗
Also known as
- alpha,alpha'-diethyl-4,4'-stilbenediol diphosphate
- diethyldihydroxystilbene diphosphate
- diethyldioxystilbene diphosphate
- diethylstilbesterol bisphosphate
- diethylstilbesterol diphosphate
- diethylstilbestrol diphosphate
- diethylstilbestrol diphosphate
- diethylstilbestrol diphosphate
- diethylstilbestrol diphosphate
- diethylstilbestrol diphosphate
- diethylstilbestryl bisphosphate
- diethylstilbestryl diphosphate
- difostilben
- fosfesterol
- fosfestrol
- fosfestrol
- fosfestrol
- fosfestrol
- fosfestrol
- fosfestrol
- fosfestrol, 99tc-labeled cpd
- fosfestrol, disodium salt, (e)-isomer
- fosfestrol, (e)-isomer
- fosfestrol, sodium salt, (e)-isomer
- fosfestrol, tetrasodium salt, (e)-isomer
- fostestrolum
- fostrolin
- honvan
- kyorin
- phosphestrol
- st-52
- stilbestrol diphosphate
- stilbestrol diphosphate
- stilphostrol
- stilphostrol
- stilphostrol
- stilphostrol