jdq443

Small moleculeexperimental

Clinical trial activity

7 trials · 4 clinical orgs · 0 marketing orgs

Phase 1
3
Phase 2
6
Phase 3
1
Phase 4
0

Earliest trial started Feb 24, 2021 (NCT04699188)

Timeline

2020s

  1. Jan 1, 2021

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2022

    Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2022

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

C=CC(=O)N1CC2(CC(n3nc(-c4ccc5c(cnn5C)c4)c(-c4c(Cl)c(C)cc5[nH]ncc45)c3C)C2)C1
Mol. weight
526.04 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05999357Phase 2Nov 30, 2023Maastricht University, Novartis
NCT05714891Phase 2Sep 15, 2023Canadian Cancer Trials Group, McGill University, Novartis
NCT05445843Phase 2Dec 6, 2022Novartis
NCT05358249Phase 1/Phase 2 (Phase 2)Oct 24, 2022Novartis
NCT05329623Phase 1May 3, 2022Novartis
NCT05132075Phase 3Mar 1, 2022Novartis
NCT04699188Phase 1/Phase 2 (Phase 2)Feb 24, 2021Novartis
Showing 7 of 7 trials
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Organizations

Research & Development (4)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
NovartisFor profit7532021
Canadian Cancer Trials GroupAcademic/Hospital1112023
Maastricht UniversityAcademic/Hospital1112023
McGill UniversityAcademic/Hospital1012023
4 organizations
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