← Mechanisms of action
EZH2
SINGLE PROTEINHomo sapiens
Preferred name: Histone-lysine N-methyltransferase EZH2 ChEMBL ↗
Linked proteins
Drugs acting on this target (13)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| cpi-0209 | Inhibitor | experimental | Small molecule | EZH2 inhibitor |
| cpi-1205 | Inhibitor | experimental | Small molecule | EZH2 inhibitor |
| gcb-002 | Inhibitor | experimental | Small molecule | EZH2 inhibitor |
| gsk2816126 | Inhibitor | experimental | Small molecule | EZH2 inhibitor |
| hh2853 | Inhibitor | experimental | Small molecule | EZH2 inhibitor |
| hm97662 | Inhibitor | experimental | Small molecule | EZH2 inhibitor |
| pf-06821497 | Inhibitor | experimental | Small molecule | EZH2 inhibitor |
| shr-2554 | Inhibitor | experimental | Small molecule | EZH2 inhibitor |
| shr2554 | Inhibitor | experimental | Small molecule | EZH2 inhibitor |
| tazemetostat (Tazverik) | Inhibitor | approved | Small molecule | Histone-lysine N-methyltransferase EZH2 inhibitor |
| tr115 | Inhibitor | experimental | Small molecule | EZH2 inhibitor |
| valemetostat (Ezharmia) | Inhibitor | experimental | Small molecule | EZH2 inhibitor |
| xnw5004 | Inhibitor | experimental | Small molecule | EZH2 inhibitor |