pf-06821497

Small moleculeexperimental

Clinical trial activity

6 trials · 1 clinical orgs · 0 marketing orgs

Phase 1
3
Phase 2
3
Phase 3
3
Phase 4
0

Earliest trial started Apr 19, 2018 (NCT03460977)

Timeline

2010s

  1. Jan 1, 2018

    Earliest Phase 1 Sponsor(trial)

2020s

  1. Jan 1, 2024

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

COc1cc(C)[nH]c(=O)c1CN1CCc2c(Cl)cc([C@H](OC)C3COC3)c(Cl)c2C1=O
Mol. weight
467.35 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07028853Phase 3Sep 28, 2025Pfizer
NCT06629779Phase 3Oct 22, 2024Pfizer
NCT06551324Phase 3Oct 21, 2024Pfizer
NCT06392230Phase 1Aug 30, 2024Pfizer
NCT05767905Phase 1Mar 17, 2023Pfizer
NCT03460977Phase 1Apr 19, 2018Pfizer
Showing 6 of 6 trials
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Organizations

Research & Development (1)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
PfizerFor profit6622018
1 organizations
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