← Mechanisms of action
GABA A receptor alpha-1/beta-1/gamma-2
PROTEIN COMPLEXHomo sapiens
Linked proteins
Drugs acting on this target (7)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| ethylenediamine | Activator | experimental | Small molecule | GABA A receptor alpha-1/beta-1/gamma-2 activator |
| zopiclone (Zimovane) | Allosteric antagonist | experimental | Small molecule | GABA A receptor alpha-1/beta-1/gamma-2 allosteric antagonist |
| ether (ether) | Antagonist | marketed | Small molecule | GABA A receptor alpha-1/beta-1/gamma-2 antagonist |
| pentylenetetrazol | Antagonist | marketed | Small molecule | GABA A receptor alpha-1/beta-1/gamma-2 antagonist |
| uc1010 | Antagonist | experimental | Small molecule | GABA A receptor alpha-1/beta-1/gamma-2 antagonist |
| ro6953958 | Modulator | experimental | Small molecule | GABA A receptor alpha-1/beta-1/gamma-2 modulator |
| zaleplon (sonata) | Positive allosteric modulator | approved | Small molecule | GABA A receptor alpha-1/beta-1/gamma-2 positive allosteric modulator |