← Mechanisms of action
Endothelin receptor, ET-A/ET-B
PROTEIN FAMILYHomo sapiens
Linked proteins
Drugs acting on this target (4)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| ambrisentan (letairis) | Antagonist | approved | Small molecule | Endothelin receptor, ET-A/ET-B antagonist |
| aprocitentan (TRYVIOTM) | Antagonist | approved | Small molecule | Endothelin receptor, ET-A/ET-B antagonist |
| bosentan (tracleer) | Antagonist | approved | Small molecule | Endothelin receptor, ET-A/ET-B antagonist |
| macitentan (opsumit) | Antagonist | approved | Small molecule | Endothelin receptor, ET-A/ET-B antagonist |