← Mechanisms of action
Hepatitis C virus serine protease, NS3/NS4A
PROTEIN COMPLEXHepatitis C virus
Linked proteins
Drugs acting on this target (21)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| danoprevir | Antagonist | experimental | Small molecule | Hepatitis C virus serine protease, NS3/NS4A antagonist |
| glecaprevir (Mavyret) | Antagonist | approved | Small molecule | Hepatitis C virus serine protease, NS3/NS4A antagonist |
| paritaprevir (viekira pak) | Antagonist | approved | Small molecule | Hepatitis C virus serine protease, NS3/NS4A antagonist |
| asunaprevir | Inhibitor | experimental | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| boceprevir (victrelis) | Inhibitor | approved | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| bzf961 | Inhibitor | experimental | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| ciluprevir | Inhibitor | experimental | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| danoprevir | Inhibitor | experimental | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| faldaprevir | Inhibitor | experimental | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| furaprevir | Inhibitor | experimental | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| glecaprevir (Mavyret) | Inhibitor | approved | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| grazoprevir (zepatier) | Inhibitor | approved | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| gs-9256 | Inhibitor | experimental | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| narlaprevir | Inhibitor | experimental | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| paritaprevir (viekira pak) | Inhibitor | approved | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| simeprevir (olysio) | Inhibitor | approved | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| sovaprevir | Inhibitor | experimental | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| telaprevir (incivek) | Inhibitor | approved | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| vaniprevir | Inhibitor | experimental | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| vedroprevir | Inhibitor | experimental | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |
| voxilaprevir (Vosevi) | Inhibitor | approved | Small molecule | Hepatitis C virus serine protease, NS3/NS4A inhibitor |