← Mechanisms of action
Vascular endothelial growth factor receptor
PROTEIN FAMILYHomo sapiens
Linked proteins
Drugs acting on this target (40)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| donafenib (Zepsun) | Antagonist | experimental | Small molecule | Vascular endothelial growth factor receptor antagonist |
| 4sc-203 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| abt-869 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| ag-013958 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| axitinib (inlyta) | Inhibitor | approved | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| bms-690514 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| brivanib alaninate | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| cediranib | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| cep 7055 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| cep-11981 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| cep5214 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| Chiauranib | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| cp-459632 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| foretinib | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| fruquintinib (Fruzaqla) | Inhibitor | approved | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| glesatinib | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| ilorasertib | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| krn 633 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| l-21649 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| lenvatinib (lenvima) | Inhibitor | approved | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| lucitanib | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| mgdc265 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| nintedanib (ofev) | Inhibitor | approved | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| osi-930 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| pazopanib (votrient) | Inhibitor | approved | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| regorafenib (stivarga) | Inhibitor | approved | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| rg1530 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| romiplostim (nplate) | Inhibitor | approved | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| sorafenib (nexavar) | Inhibitor | approved | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| su14813 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| sulfatinib | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| sunitinib (sutent) | Inhibitor | approved | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| surufatinib | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| tak-593 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| tivozanib (Fotivda) | Inhibitor | approved | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| vandetanib (caprelsa) | Inhibitor | approved | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| vatalanib | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| x-82 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| xl820 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |
| xl999 | Inhibitor | experimental | Small molecule | Vascular endothelial growth factor receptor inhibitor |