← Mechanisms of action
Protein kinase C (PKC)
PROTEIN FAMILYHomo sapiens
Linked proteins
- Serine/threonine-protein kinase D3 (PRKD3) ↗
- Protein kinase C iota type (PRKCI) ↗
- Protein kinase C alpha type (PRKCA) ↗
- Protein kinase C gamma type (PRKCG) ↗
- Protein kinase C delta type (PRKCD) ↗
- Protein kinase C beta type (PRKCB) ↗
- Protein kinase C zeta type (PRKCZ) ↗
- Protein kinase C epsilon type (PRKCE) ↗
- Protein kinase C eta type (PRKCH) ↗
- Serine/threonine-protein kinase D1 (PRKD1) ↗
- Protein kinase C theta type (PRKCQ) ↗
Drugs acting on this target (6)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| 7-hydroxystaurosporine | Inhibitor | experimental | Small molecule | Protein kinase C (PKC) inhibitor |
| c1k | Inhibitor | experimental | Small molecule | Protein kinase C (PKC) inhibitor |
| cep2563 | Inhibitor | experimental | Small molecule | Protein kinase C (PKC) inhibitor |
| gsk-690693 | Inhibitor | experimental | Small molecule | Protein kinase C (PKC) inhibitor |
| midostaurin (rydapt) | Inhibitor | approved | Small molecule | Protein kinase C (PKC) inhibitor |
| sotrastaurin | Inhibitor | experimental | Small molecule | Protein kinase C (PKC) inhibitor |