← Mechanisms of action
ESR1
SINGLE PROTEINOvis aries
Preferred name: Estrogen receptor ChEMBL ↗
Linked proteins
Drugs acting on this target (8)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| conjugated estrogens/medroxyprogesterone acetate | Agonist | approved | Small molecule | ESR1 agonist |
| estetrol (NEXTSTELLIS) | Agonist | approved | Small molecule | ESR1 agonist |
| estrogens, esterified (menrium component estrogens, esterified) | Agonist | approved | Small molecule | ESR1 agonist |
| estropipate (ogen) | Agonist | approved | Small molecule | ESR1 agonist |
| tibolone (xyvion) | Agonist | experimental | Small molecule | ESR1 agonist |
| elacestrant (Orserdu) | Antagonist | approved | Small molecule | ESR1 antagonist |
| fluoroestradiol (Cerianna) | Binding agent | approved | Small molecule | ESR1 binding agent |
| raloxifene (evista) | Modulator | approved | Small molecule | ESR1 modulator |