CDEK
← Mechanisms of action

IL1B

SINGLE PROTEINHomo sapiens
Preferred name: Interleukin-1 beta ChEMBL ↗

Linked proteins

Drugs acting on this target (16)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
ak114AntagonistexperimentalmAbIL1B
anakinra (Kineret)AntagonistapprovedRecombinant proteinIL1B antagonist
avtx-009AntagonistexperimentalmAbIL1B antagonist
ssgj-613AntagonistexperimentalmAbIL1B
cyt013-il1bqbImmunity, activeexperimentalVaccineIL1B immunity, active
abt-981Immunity, passiveexperimentalmAbIL1B immunity, passive
abt-981InhibitorexperimentalmAbInterleukin-1 beta inhibitor
canakinumab (ilaris)InhibitorapprovedmAbIL1B inhibitor
cdp-484InhibitorexperimentalmAbIL1B inhibitor
fl-101InhibitorexperimentalSmall moleculeIL1B inhibitor
gevokizumabInhibitorexperimentalmAbIL1B inhibitor
GoflikiceptInhibitorexperimentalSmall moleculeIL1B inhibitor
ly2189102InhibitorexperimentalmAbIL1B inhibitor
rilonacept (arcalyst)InhibitorapprovedRecombinant proteinIL1B inhibitor
zenuzolacInhibitorexperimentalSmall moleculeIL1B inhibitor
gevokizumabNegative allosteric modulatorexperimentalmAbIL1B negative allosteric modulator